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Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport.
Florido J, Martinez-Ruiz L, Rodriguez-Santana C, López-Rodríguez A, Hidalgo-Gutiérrez A, Cottet-Rousselle C, Lamarche F, Schlattner U, Guerra-Librero A, Aranda-Martínez P, Acuña-Castroviejo D, López LC, Escames G. Florido J, et al. Among authors: rodriguez santana c. J Pineal Res. 2022 Oct;73(3):e12824. doi: 10.1111/jpi.12824. Epub 2022 Aug 28. J Pineal Res. 2022. PMID: 35986493 Free PMC article.
Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy.
Fernandez-Gil BI, Guerra-Librero A, Shen YQ, Florido J, Martínez-Ruiz L, García-López S, Adan C, Rodríguez-Santana C, Acuña-Castroviejo D, Quiñones-Hinojosa A, Fernández-Martínez J, Abdel Moneim AE, López LC, Rodríguez Ferrer JM, Escames G. Fernandez-Gil BI, et al. Oxid Med Cell Longev. 2019 Feb 28;2019:7187128. doi: 10.1155/2019/7187128. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 30944696 Free PMC article.
Protective Effects of Melatonin on the Skin: Future Perspectives.
Rusanova I, Martínez-Ruiz L, Florido J, Rodríguez-Santana C, Guerra-Librero A, Acuña-Castroviejo D, Escames G. Rusanova I, et al. Int J Mol Sci. 2019 Oct 8;20(19):4948. doi: 10.3390/ijms20194948. Int J Mol Sci. 2019. PMID: 31597233 Free PMC article. Review.
Melatonin Targets Metabolism in Head and Neck Cancer Cells by Regulating Mitochondrial Structure and Function.
Guerra-Librero A, Fernandez-Gil BI, Florido J, Martinez-Ruiz L, Rodríguez-Santana C, Shen YQ, García-Verdugo JM, López-Rodríguez A, Rusanova I, Quiñones-Hinojosa A, Acuña-Castroviejo D, Marruecos J, De Haro T, Escames G. Guerra-Librero A, et al. Among authors: rodriguez santana c. Antioxidants (Basel). 2021 Apr 14;10(4):603. doi: 10.3390/antiox10040603. Antioxidants (Basel). 2021. PMID: 33919790 Free PMC article.
Role of Melatonin in Cancer: Effect on Clock Genes.
Rodríguez-Santana C, Florido J, Martínez-Ruiz L, López-Rodríguez A, Acuña-Castroviejo D, Escames G. Rodríguez-Santana C, et al. Int J Mol Sci. 2023 Jan 18;24(3):1919. doi: 10.3390/ijms24031919. Int J Mol Sci. 2023. PMID: 36768253 Free PMC article. Review.
Chronodisruption and Loss of Melatonin Rhythm, Associated with Alterations in Daily Motor Activity and Mitochondrial Dynamics in Parkinsonian Zebrafish, Are Corrected by Melatonin Treatment.
Aranda-Martínez P, Fernández-Martínez J, Ramírez-Casas Y, Rodríguez-Santana C, Rusanova I, Escames G, Acuña-Castroviejo D. Aranda-Martínez P, et al. Among authors: rodriguez santana c. Antioxidants (Basel). 2023 Apr 18;12(4):954. doi: 10.3390/antiox12040954. Antioxidants (Basel). 2023. PMID: 37107331 Free PMC article.
Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress.
Martinez-Ruiz L, Florido J, Rodriguez-Santana C, López-Rodríguez A, Guerra-Librero A, Fernández-Gil BI, García-Tárraga P, Garcia-Verdugo JM, Oppel F, Sudhoff H, Sánchez-Porras D, Ten-Steve A, Fernández-Martínez J, González-García P, Rusanova I, Acuña-Castroviejo D, Carriel V, Escames G. Martinez-Ruiz L, et al. Among authors: rodriguez santana c. Biomed Pharmacother. 2023 Nov;167:115518. doi: 10.1016/j.biopha.2023.115518. Epub 2023 Sep 15. Biomed Pharmacother. 2023. PMID: 37717534 Free article.
14 results