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Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB1R) "Cis-On" Agonist.
ACS Chem Neurosci. 2022 Aug 17;13(16):2410-2435. doi: 10.1021/acschemneuro.2c00160. Epub 2022 Jul 26.
ACS Chem Neurosci. 2022.
PMID: 35881914
"Photo-Rimonabant": Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar "Cis-On" CB1R Antagonist.
Rodríguez-Soacha DA, Fender J, Ramírez YA, Collado JA, Muñoz E, Maitra R, Sotriffer C, Lorenz K, Decker M.
Rodríguez-Soacha DA, et al.
ACS Chem Neurosci. 2021 May 5;12(9):1632-1647. doi: 10.1021/acschemneuro.1c00086. Epub 2021 Apr 15.
ACS Chem Neurosci. 2021.
PMID: 33856764
Free PMC article.
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Multi-target-directed-ligands acting as enzyme inhibitors and receptor ligands.
Rodríguez-Soacha DA, Scheiner M, Decker M.
Rodríguez-Soacha DA, et al.
Eur J Med Chem. 2019 Oct 15;180:690-706. doi: 10.1016/j.ejmech.2019.07.040. Epub 2019 Jul 12.
Eur J Med Chem. 2019.
PMID: 31401465
Review.
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