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Page 1
Discovery of Potent Dual PPARα Agonists/CB1 Ligands.
Pérez-Fernández R, Fresno N, Macías-González M, Elguero J, Decara J, Girón R, Rodríguez-Álvarez A, Martín MI, Rodríguez de Fonseca F, Goya P. Pérez-Fernández R, et al. Among authors: rodriguez de fonseca f, rodriguez alvarez a. ACS Med Chem Lett. 2011 Sep 16;2(11):793-7. doi: 10.1021/ml200091q. eCollection 2011 Nov 10. ACS Med Chem Lett. 2011. PMID: 24936232 Free PMC article.
Discovery of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1h-1,2,4-triazole, a novel in vivo cannabinoid antagonist containing a 1,2,4-triazole motif.
Jagerovic N, Hernandez-Folgado L, Alkorta I, Goya P, Navarro M, Serrano A, Rodriguez de Fonseca F, Dannert MT, Alsasua A, Suardiaz M, Pascual D, Martín MI. Jagerovic N, et al. Among authors: rodriguez de fonseca f. J Med Chem. 2004 May 20;47(11):2939-42. doi: 10.1021/jm031099y. J Med Chem. 2004. PMID: 15139773
Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole--LH 21.
Pavon FJ, Bilbao A, Hernández-Folgado L, Cippitelli A, Jagerovic N, Abellán G, Rodríguez-Franco MA, Serrano A, Macias M, Gómez R, Navarro M, Goya P, Rodríguez de Fonseca F. Pavon FJ, et al. Among authors: rodriguez franco ma, rodriguez de fonseca f. Neuropharmacology. 2006 Aug;51(2):358-66. doi: 10.1016/j.neuropharm.2006.03.029. Epub 2006 Jun 5. Neuropharmacology. 2006. PMID: 16750544
Enhanced markers of oxidative stress, altered antioxidants and NADPH-oxidase activation in brains from Fragile X mental retardation 1-deficient mice, a pathological model for Fragile X syndrome.
el Bekay R, Romero-Zerbo Y, Decara J, Sanchez-Salido L, Del Arco-Herrera I, Rodríguez-de Fonseca F, de Diego-Otero Y. el Bekay R, et al. Among authors: rodriguez de fonseca f, de diego otero y. Eur J Neurosci. 2007 Dec;26(11):3169-80. doi: 10.1111/j.1460-9568.2007.05939.x. Epub 2007 Nov 14. Eur J Neurosci. 2007. PMID: 18005058
Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency.
de Diego-Otero Y, Romero-Zerbo Y, el Bekay R, Decara J, Sanchez L, Rodriguez-de Fonseca F, del Arco-Herrera I. de Diego-Otero Y, et al. Among authors: rodriguez de fonseca f. Neuropsychopharmacology. 2009 Mar;34(4):1011-26. doi: 10.1038/npp.2008.152. Epub 2008 Oct 8. Neuropsychopharmacology. 2009. PMID: 18843266
Antiobesity designed multiple ligands: Synthesis of pyrazole fatty acid amides and evaluation as hypophagic agents.
Alvarado M, Goya P, Macías-González M, Pavón FJ, Serrano A, Jagerovic N, Elguero J, Gutiérrez-Rodríguez A, García-Granda S, Suardíaz M, Rodríguez de Fonseca F. Alvarado M, et al. Among authors: rodriguez de fonseca f. Bioorg Med Chem. 2008 Dec 1;16(23):10098-105. doi: 10.1016/j.bmc.2008.10.023. Epub 2008 Oct 14. Bioorg Med Chem. 2008. PMID: 18952442
Synthesis of fatty acid amides of catechol metabolites that exhibit antiobesity properties.
Almeida B, Joglar J, Luque Rojas MJ, Decara JM, Bermúdez-Silva FJ, Macias-González M, Fitó M, Romero-Cuevas M, Farré M, Covas MI, Rodríguez de Fonseca F, de la Torre R. Almeida B, et al. Among authors: de la torre r, rodriguez de fonseca f. ChemMedChem. 2010 Oct 4;5(10):1781-7. doi: 10.1002/cmdc.201000161. ChemMedChem. 2010. PMID: 20718074
Anti-obesity efficacy of LH-21, a cannabinoid CB(1) receptor antagonist with poor brain penetration, in diet-induced obese rats.
Alonso M, Serrano A, Vida M, Crespillo A, Hernandez-Folgado L, Jagerovic N, Goya P, Reyes-Cabello C, Perez-Valero V, Decara J, Macías-González M, Bermúdez-Silva FJ, Suárez J, Rodríguez de Fonseca F, Pavón FJ. Alonso M, et al. Among authors: rodriguez de fonseca f. Br J Pharmacol. 2012 Apr;165(7):2274-91. doi: 10.1111/j.1476-5381.2011.01698.x. Br J Pharmacol. 2012. PMID: 21951309 Free PMC article.
307 results