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Page 1
Plitidepsin as an Immunomodulator against Respiratory Viral Infections.
Losada A, Izquierdo-Useros N, Aviles P, Vergara-Alert J, Latino I, Segalés J, Gonzalez SF, Cuevas C, Raïch-Regué D, Muñoz-Alonso MJ, Perez-Zsolt D, Muñoz-Basagoiti J, Rodon J, Chang LA, Warang P, Singh G, Brustolin M, Cantero G, Roca N, Pérez M, Bustos-Morán E, White K, Schotsaert M, García-Sastre A. Losada A, et al. Among authors: rodon j. J Immunol. 2024 Apr 15;212(8):1307-1318. doi: 10.4049/jimmunol.2300426. J Immunol. 2024. PMID: 38416036
Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen.
Rodon J, Muñoz-Basagoiti J, Perez-Zsolt D, Noguera-Julian M, Paredes R, Mateu L, Quiñones C, Perez C, Erkizia I, Blanco I, Valencia A, Guallar V, Carrillo J, Blanco J, Segalés J, Clotet B, Vergara-Alert J, Izquierdo-Useros N. Rodon J, et al. Front Pharmacol. 2021 Mar 25;12:646676. doi: 10.3389/fphar.2021.646676. eCollection 2021. Front Pharmacol. 2021. PMID: 33841165 Free PMC article.
Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.
Varona JF, Landete P, Lopez-Martin JA, Estrada V, Paredes R, Guisado-Vasco P, Fernandez de Orueta L, Torralba M, Fortun J, Vates R, Barberan J, Clotet B, Ancochea J, Carnevali D, Cabello N, Porras L, Gijon P, Monereo A, Abad D, Zuñiga S, Sola I, Rodon J, Vergara-Alert J, Izquierdo-Useros N, Fudio S, Pontes MJ, de Rivas B, Giron de Velasco P, Nieto A, Gomez J, Aviles P, Lubomirov R, Belgrano A, Sopesen B, White KM, Rosales R, Yildiz S, Reuschl AK, Thorne LG, Jolly C, Towers GJ, Zuliani-Alvarez L, Bouhaddou M, Obernier K, McGovern BL, Rodriguez ML, Enjuanes L, Fernandez-Sousa JM, Krogan NJ, Jimeno JM, Garcia-Sastre A. Varona JF, et al. Among authors: rodon j. Life Sci Alliance. 2022 Jan 10;5(4):e202101200. doi: 10.26508/lsa.202101200. Print 2022 Apr. Life Sci Alliance. 2022. PMID: 35012962 Free PMC article. Clinical Trial.
Unraveling the antiviral activity of plitidepsin against SARS-CoV-2 by subcellular and morphological analysis.
Sachse M, Tenorio R, Fernández de Castro I, Muñoz-Basagoiti J, Perez-Zsolt D, Raïch-Regué D, Rodon J, Losada A, Avilés P, Cuevas C, Paredes R, Segalés J, Clotet B, Vergara-Alert J, Izquierdo-Useros N, Risco C. Sachse M, et al. Among authors: rodon j. Antiviral Res. 2022 Apr;200:105270. doi: 10.1016/j.antiviral.2022.105270. Epub 2022 Feb 26. Antiviral Res. 2022. PMID: 35231500 Free PMC article.
Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant.
Ávila-Nieto C, Vergara-Alert J, Amengual-Rigo P, Ainsua-Enrich E, Brustolin M, Rodríguez de la Concepción ML, Pedreño-Lopez N, Rodon J, Urrea V, Pradenas E, Marfil S, Ballana E, Riveira-Muñoz E, Pérez M, Roca N, Tarrés-Freixas F, Carabelli J, Cantero G, Pons-Grífols A, Rovirosa C, Aguilar-Gurrieri C, Ortiz R, Barajas A, Trinité B, Lepore R, Muñoz-Basagoiti J, Perez-Zsolt D, Izquierdo-Useros N, Valencia A, Blanco J, Clotet B, Guallar V, Segalés J, Carrillo J. Ávila-Nieto C, et al. Among authors: rodon j. Front Immunol. 2023 Dec 4;14:1291972. doi: 10.3389/fimmu.2023.1291972. eCollection 2023. Front Immunol. 2023. PMID: 38124756 Free PMC article.
Detection of SARS-CoV-2 in a cat owned by a COVID-19-affected patient in Spain.
Segalés J, Puig M, Rodon J, Avila-Nieto C, Carrillo J, Cantero G, Terrón MT, Cruz S, Parera M, Noguera-Julián M, Izquierdo-Useros N, Guallar V, Vidal E, Valencia A, Blanco I, Blanco J, Clotet B, Vergara-Alert J. Segalés J, et al. Among authors: rodon j. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24790-24793. doi: 10.1073/pnas.2010817117. Epub 2020 Sep 18. Proc Natl Acad Sci U S A. 2020. PMID: 32948692 Free PMC article.
Pigs are not susceptible to SARS-CoV-2 infection but are a model for viral immunogenicity studies.
Vergara-Alert J, Rodon J, Carrillo J, Te N, Izquierdo-Useros N, Rodríguez de la Concepción ML, Ávila-Nieto C, Guallar V, Valencia A, Cantero G, Blanco J, Clotet B, Bensaid A, Segalés J. Vergara-Alert J, et al. Among authors: rodon j. Transbound Emerg Dis. 2021 Jul;68(4):1721-1725. doi: 10.1111/tbed.13861. Epub 2020 Oct 23. Transbound Emerg Dis. 2021. PMID: 33007154 Free PMC article.
Protection against reinfection with D614- or G614-SARS-CoV-2 isolates in golden Syrian hamster.
Brustolin M, Rodon J, Rodríguez de la Concepción ML, Ávila-Nieto C, Cantero G, Pérez M, Te N, Noguera-Julián M, Guallar V, Valencia A, Roca N, Izquierdo-Useros N, Blanco J, Clotet B, Bensaid A, Carrillo J, Vergara-Alert J, Segalés J. Brustolin M, et al. Among authors: rodon j. Emerg Microbes Infect. 2021 Dec;10(1):797-809. doi: 10.1080/22221751.2021.1913974. Emerg Microbes Infect. 2021. PMID: 33825619 Free PMC article.
229 results