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Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trials.
Mayer-Hamblett N, Ratjen F, Russell R, Donaldson SH, Riekert KA, Sawicki GS, Odem-Davis K, Young JK, Rosenbluth D, Taylor-Cousar JL, Goss CH, Retsch-Bogart G, Clancy JP, Genatossio A, O'Sullivan BP, Berlinski A, Millard SL, Omlor G, Wyatt CA, Moffett K, Nichols DP, Gifford AH; SIMPLIFY Study Group. Mayer-Hamblett N, et al. Lancet Respir Med. 2023 Apr;11(4):329-340. doi: 10.1016/S2213-2600(22)00434-9. Epub 2022 Nov 4. Lancet Respir Med. 2023. PMID: 36343646 Free PMC article. Clinical Trial.
Neuroinflammation is highest in areas of disease progression in semantic dementia.
Pascual B, Funk Q, Zanotti-Fregonara P, Cykowski MD, Veronese M, Rockers E, Bradbury K, Yu M, Nakawah MO, Román GC, Schulz PE, Arumanayagam AS, Beers D, Faridar A, Fujita M, Appel SH, Masdeu JC. Pascual B, et al. Among authors: rockers e. Brain. 2021 Jun 22;144(5):1565-1575. doi: 10.1093/brain/awab057. Brain. 2021. PMID: 33824991
Multimodal 18F-AV-1451 and MRI Findings in Nonfluent Variant of Primary Progressive Aphasia: Possible Insights on Nodal Propagation of Tau Protein Across the Syntactic Network.
Pascual B, Funk Q, Zanotti-Fregonara P, Pal N, Rockers E, Yu M, Spann B, Román GC, Schulz PE, Karmonik C, Appel SH, Masdeu JC. Pascual B, et al. Among authors: rockers e. J Nucl Med. 2020 Feb;61(2):263-269. doi: 10.2967/jnumed.118.225508. Epub 2019 Jul 26. J Nucl Med. 2020. PMID: 31350322 Free PMC article.