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First-line single-agent panitumumab in frail elderly patients with wild-type KRAS metastatic colorectal cancer and poor prognostic factors: A phase II study of the Spanish Cooperative Group for the Treatment of Digestive Tumours.
Sastre J, Massuti B, Pulido G, Guillén-Ponce C, Benavides M, Manzano JL, Reboredo M, Rivera F, Grávalos C, Safont MJ, Martínez Villacampa M, Llovet P, Dotor E, Díaz-Rubio E, Aranda E; Spanish Cooperative Group for the Treatment of Digestive Tumours TTD. Sastre J, et al. Eur J Cancer. 2015 Jul;51(11):1371-80. doi: 10.1016/j.ejca.2015.04.013. Epub 2015 May 8. Eur J Cancer. 2015. PMID: 25963019 Clinical Trial.
Identification of new SNPs associated with severe toxicity to capecitabine.
Pellicer M, García-González X, García MI, Robles L, Grávalos C, García-Alfonso P, Pachón V, Longo F, Martínez V, Blanco C, Iglesias I, Sanjurjo M, López-Fernández LA. Pellicer M, et al. Among authors: robles l. Pharmacol Res. 2017 Jun;120:133-137. doi: 10.1016/j.phrs.2017.03.021. Epub 2017 Mar 27. Pharmacol Res. 2017. PMID: 28347776
Use of exome sequencing to determine the full profile of genetic variants in the fluoropyrimidine pathway in colorectal cancer patients affected by severe toxicity.
Pellicer M, García-González X, García MI, Blanco C, García-Alfonso P, Robles L, Grávalos C, Rueda D, Martínez J, Pachón V, Longo F, Martínez V, Iglesias I, Salvador S, Sanjurjo M, López-Fernández LA. Pellicer M, et al. Among authors: robles l. Pharmacogenomics. 2017 Aug;18(13):1215-1223. doi: 10.2217/pgs-2017-0118. Epub 2017 Jul 26. Pharmacogenomics. 2017. PMID: 28745575
A Randomized Phase II Study of Axitinib as Maintenance Therapy After First-line Treatment for Metastatic Colorectal Cancer.
Grávalos C, Carrato A, Tobeña M, Rodriguez-Garrote M, Soler G, Vieitez JM, Robles L, Valladares-Ayerbes M, Polo E, Limón ML, Safont MJ, Martínez de Castro E, García-Alfonso P, Aranda E; Spanish Cooperative Group for the Treatment of Digestive Tumors (TTD). Grávalos C, et al. Among authors: robles l. Clin Colorectal Cancer. 2018 Jun;17(2):e323-e329. doi: 10.1016/j.clcc.2018.02.004. Epub 2018 Feb 17. Clin Colorectal Cancer. 2018. PMID: 29551560 Clinical Trial.
Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan.
Salvador-Martín S, García-González X, García MI, Blanco C, García-Alfonso P, Robles L, Grávalos C, Pachón V, Longo F, Martínez V, Sanjurjo-Sáez M, López-Fernández LA. Salvador-Martín S, et al. Among authors: robles l. Pharmacol Res. 2018 Oct;136:133-139. doi: 10.1016/j.phrs.2018.08.026. Epub 2018 Sep 11. Pharmacol Res. 2018. PMID: 30213564
Comments on: "Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan".
Salvador-Martiín S, García-González X, García MI, Blanco C, García-Alfonso P, Robles L, Grávalos C, Pachón V, Longo F, Martínez V, Sanjurjo-Sáez M, López-Fernández LA. Salvador-Martiín S, et al. Among authors: robles l. Pharmacol Res. 2019 Jul;145:104288. doi: 10.1016/j.phrs.2019.104288. Epub 2019 May 26. Pharmacol Res. 2019. PMID: 31141714 No abstract available.
New DPYD variants causing DPD deficiency in patients treated with fluoropyrimidine.
García-González X, Kaczmarczyk B, Abarca-Zabalía J, Thomas F, García-Alfonso P, Robles L, Pachón V, Vaz Á, Salvador-Martín S, Sanjurjo-Sáez M, López-Fernández LA. García-González X, et al. Among authors: robles l. Cancer Chemother Pharmacol. 2020 Jul;86(1):45-54. doi: 10.1007/s00280-020-04093-1. Epub 2020 Jun 11. Cancer Chemother Pharmacol. 2020. PMID: 32529295
233 results