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Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus.
Mousnier A, Bell AS, Swieboda DP, Morales-Sanfrutos J, Pérez-Dorado I, Brannigan JA, Newman J, Ritzefeld M, Hutton JA, Guedán A, Asfor AS, Robinson SW, Hopkins-Navratilova I, Wilkinson AJ, Johnston SL, Leatherbarrow RJ, Tuthill TJ, Solari R, Tate EW. Mousnier A, et al. Among authors: robinson sw. Nat Chem. 2018 Jun;10(6):599-606. doi: 10.1038/s41557-018-0039-2. Epub 2018 May 14. Nat Chem. 2018. PMID: 29760414 Free PMC article.
Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors.
Henderson SH, Sorrell F, Bennett J, Fedorov O, Hanley MT, Godoi PH, Ruela de Sousa R, Robinson S, Ashall-Kelly A, Hopkins Navratilova I, Walter DS, Elkins JM, Ward SE. Henderson SH, et al. J Med Chem. 2021 Aug 12;64(15):11709-11728. doi: 10.1021/acs.jmedchem.1c01115. Epub 2021 Aug 3. J Med Chem. 2021. PMID: 34342227 Free PMC article.
Identification of Inhibitors of the Schistosoma mansoni VKR2 Kinase Domain.
Mathavan I, Liu LJ, Robinson SW, El-Sakkary N, Elatico AJJ, Gomez D, Nellas R, Owens RJ, Zuercher W, Navratilova I, Caffrey CR, Beis K. Mathavan I, et al. Among authors: robinson sw. ACS Med Chem Lett. 2022 Oct 5;13(11):1715-1722. doi: 10.1021/acsmedchemlett.2c00248. eCollection 2022 Nov 10. ACS Med Chem Lett. 2022. PMID: 36385939 Free PMC article.
Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19.
Redhead MA, Owen CD, Brewitz L, Collette AH, Lukacik P, Strain-Damerell C, Robinson SW, Collins PM, Schäfer P, Swindells M, Radoux CJ, Hopkins IN, Fearon D, Douangamath A, von Delft F, Malla TR, Vangeel L, Vercruysse T, Thibaut J, Leyssen P, Nguyen TT, Hull M, Tumber A, Hallett DJ, Schofield CJ, Stuart DI, Hopkins AL, Walsh MA. Redhead MA, et al. Among authors: robinson sw. Sci Rep. 2021 Jun 24;11(1):13208. doi: 10.1038/s41598-021-92416-4. Sci Rep. 2021. PMID: 34168183 Free PMC article.
Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates.
Cahill ST, Tyrrell JM, Navratilova IH, Calvopiña K, Robinson SW, Lohans CT, McDonough MA, Cain R, Fishwick CWG, Avison MB, Walsh TR, Schofield CJ, Brem J. Cahill ST, et al. Among authors: robinson sw. Biochim Biophys Acta Gen Subj. 2019 Apr;1863(4):742-748. doi: 10.1016/j.bbagen.2019.02.004. Epub 2019 Feb 7. Biochim Biophys Acta Gen Subj. 2019. PMID: 30738906 Free article.
Frailty Measures of Patient-reported Activity and Fatigue May Predict 1-year Outcomes in Ambulatory Advanced Heart Failure: A Report From the REVIVAL Registry.
Lala A, Shah P, Khalatbari S, Yosef M, Mountis MM, Robinson SW, Lanfear DE, Estep JD, Jeffries N, Taddei-Peters WC, Stevenson LW, Richards B, Mann DL, Mancini DM, Stewart GC, Aaronson KD. Lala A, et al. Among authors: robinson sw. J Card Fail. 2022 May;28(5):765-774. doi: 10.1016/j.cardfail.2021.10.014. Epub 2021 Dec 25. J Card Fail. 2022. PMID: 34961663
78 results