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821 results

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In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (IWGT).
Beevers C, Uno Y, Meurer K, Hamada S, Hashimoto K, Kirkland D, LeBaron MJ, Le Curieux F, Le Hegarat L, Martus HJ, Masumura K, Ohyama W, Roberts DJ, Vasquez M, Whitwell J, Witt KL. Beevers C, et al. Among authors: roberts dj. Environ Mol Mutagen. 2023 Nov 9. doi: 10.1002/em.22578. Online ahead of print. Environ Mol Mutagen. 2023. PMID: 37942839 Review.
Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT).
Dertinger SD, Li D, Beevers C, Douglas GR, Heflich RH, Lovell DP, Roberts DJ, Smith R, Uno Y, Williams A, Witt KL, Zeller A, Zhou C. Dertinger SD, et al. Among authors: roberts dj. Environ Mol Mutagen. 2023 Apr 25:10.1002/em.22541. doi: 10.1002/em.22541. Online ahead of print. Environ Mol Mutagen. 2023. PMID: 37097075 Review.
A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.
Kirkland D, Levy DD, LeBaron MJ, Aardema MJ, Beevers C, Bhalli J, Douglas GR, Escobar PA, Farabaugh CS, Guerard M, Johnson GE, Kulkarni R, Le Curieux F, Long AS, Lott J, Lovell DP, Luijten M, Marchetti F, Nicolette JJ, Pfuhler S, Roberts DJ, Stankowski LF Jr, Thybaud V, Weiner SK, Williams A, Witt KL, Young R. Kirkland D, et al. Among authors: roberts dj. Mutat Res Genet Toxicol Environ Mutagen. 2019 Mar;839:21-35. doi: 10.1016/j.mrgentox.2019.01.007. Epub 2019 Jan 18. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 30744809 Free PMC article.
Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose-response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose-response data.
Chepelev N, Long AS, Beal M, Barton-Maclaren T, Johnson G, Dearfield KL, Roberts DJ, van Benthem J, White P. Chepelev N, et al. Among authors: roberts dj. Environ Mol Mutagen. 2023 Jan;64(1):4-15. doi: 10.1002/em.22517. Epub 2023 Jan 6. Environ Mol Mutagen. 2023. PMID: 36345771 Free PMC article.
Application of the adverse outcome pathway framework to genotoxic modes of action.
Sasaki JC, Allemang A, Bryce SM, Custer L, Dearfield KL, Dietz Y, Elhajouji A, Escobar PA, Fornace AJ Jr, Froetschl R, Galloway S, Hemmann U, Hendriks G, Li HH, Luijten M, Ouedraogo G, Peel L, Pfuhler S, Roberts DJ, Thybaud V, van Benthem J, Yauk CL, Schuler M. Sasaki JC, et al. Among authors: roberts dj. Environ Mol Mutagen. 2020 Jan;61(1):114-134. doi: 10.1002/em.22339. Epub 2019 Oct 31. Environ Mol Mutagen. 2020. PMID: 31603995
AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations.
Cho E, Allemang A, Audebert M, Chauhan V, Dertinger S, Hendriks G, Luijten M, Marchetti F, Minocherhomji S, Pfuhler S, Roberts DJ, Trenz K, Yauk CL. Cho E, et al. Among authors: roberts dj. Environ Mol Mutagen. 2022 Mar;63(3):118-134. doi: 10.1002/em.22479. Epub 2022 May 3. Environ Mol Mutagen. 2022. PMID: 35315142 Free PMC article.
821 results