Roberts D - Search Results

1

A comparison of the lowest effective concentration in culture media for detection of chromosomal damage in vitro and in blood or plasma for detection of micronuclei in vivo.

Kirkland D, Whitwell J, Smith R, Hashimoto K, Ji Z, Kenny J, Koyama N, Lovell DP, Martus HJ, Meurer K, Roberts D, Takeiri A, Uno Y, van der Leede BJ, White P, Zeller A. Kirkland D, et al. Among authors: roberts d. Mutat Res Genet Toxicol Environ Mutagen. 2022 Jul-Aug;879-880:503503. doi: 10.1016/j.mrgentox.2022.503503. Epub 2022 May 28. Mutat Res Genet Toxicol Environ Mutagen. 2022. PMID: 35914859 Free article.

2

Thrombin active site inhibitors: chemical synthesis, in vitro and in vivo pharmacological profile of a novel and selective agent BMS-189090 and analogues.

Das J, Kimball SD, Reid JA, Wang TC, Lau WF, Roberts DG, Seiler SM, Schumacher WA, Ogletree ML. Das J, et al. Bioorg Med Chem Lett. 2002 Jan 7;12(1):41-4. doi: 10.1016/s0960-894x(01)00664-3. Bioorg Med Chem Lett. 2002. PMID: 11738569

3

Retro-binding thrombin active site inhibitors: identification of an orally active inhibitor of thrombin catalytic activity.

Iwanowicz EJ, Kimball SD, Lin J, Lau W, Han WC, Wang TC, Roberts DG, Schumacher WA, Ogletree ML, Seiler SM. Iwanowicz EJ, et al. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3183-6. doi: 10.1016/s0960-894x(02)00651-0. Bioorg Med Chem Lett. 2002. PMID: 12372529

4

Retro-binding tripeptide thrombin active-site inhibitors: discovery, synthesis, and molecular modeling.

Iwanowicz EJ, Lau WF, Lin J, Roberts DG, Seiler SM. Iwanowicz EJ, et al. Among authors: roberts dg. J Med Chem. 1994 Jul 8;37(14):2122-4. doi: 10.1021/jm00040a001. J Med Chem. 1994. PMID: 8035417 No abstract available.

5

The secondary drying and the fate of organic solvents for spray dried dispersion drug product.

Hsieh DS, Yue H, Nicholson SJ, Roberts D, Schild R, Gamble JF, Lindrud M. Hsieh DS, et al. Among authors: roberts d. Pharm Res. 2015 May;32(5):1804-16. doi: 10.1007/s11095-014-1577-y. Epub 2014 Dec 17. Pharm Res. 2015. PMID: 25515491

6

1,2-Benzisothiazol-3-one 1,1-dioxide inhibitors of human mast cell tryptase.

Combrink KD, Gülgeze HB, Meanwell NA, Pearce BC, Zulan P, Bisacchi GS, Roberts DG, Stanley P, Seiler SM. Combrink KD, et al. Among authors: roberts dg. J Med Chem. 1998 Nov 19;41(24):4854-60. doi: 10.1021/jm9804580. J Med Chem. 1998. PMID: 9822554

7

Solid-phase synthesis of benzisothiazolones as serine protease inhibitors.

Yu KL, Civiello R, Roberts DG, Seiler SM, Meanwell NA. Yu KL, et al. Among authors: roberts dg. Bioorg Med Chem Lett. 1999 Mar 8;9(5):663-6. doi: 10.1016/s0960-894x(99)00078-5. Bioorg Med Chem Lett. 1999. PMID: 10201825

8

Lack of an effect of nefazodone on the pharmacokinetics and pharmacodynamics of theophylline during concurrent administration in patients with chronic obstructive pulmonary disease.

Dockens RC, Rapoport D, Roberts D, Greene DS, Barbhaiya RH. Dockens RC, et al. Among authors: roberts d. Br J Clin Pharmacol. 1995 Dec;40(6):598-601. doi: 10.1111/j.1365-2125.1995.tb05806.x. Br J Clin Pharmacol. 1995. PMID: 8703669 Free PMC article. Clinical Trial.

9

Structure of a retro-binding peptide inhibitor complexed with human alpha-thrombin.

Tabernero L, Chang CY, Ohringer SL, Lau WF, Iwanowicz EJ, Han WC, Wang TC, Seiler SM, Roberts DG, Sack JS. Tabernero L, et al. Among authors: roberts dg. J Mol Biol. 1995 Feb 10;246(1):14-20. doi: 10.1006/jmbi.1994.0060. J Mol Biol. 1995. PMID: 7853394

10

Molecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.

Das J, Kimball SD, Hall SE, Han WC, Iwanowicz E, Lin J, Moquin RV, Reid JA, Sack JS, Malley MF, Chang CY, Chong S, Wang-Iverson DB, Roberts DG, Seiler SM, Schumacher WA, Ogletree ML. Das J, et al. Bioorg Med Chem Lett. 2002 Jan 7;12(1):45-9. doi: 10.1016/s0960-894x(01)00667-9. Bioorg Med Chem Lett. 2002. PMID: 11738570

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