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526 results

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A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, Han J, Ryu S, Tare A, Zhu Y, Hudgins A, Atzmon G, Barzilai N, Wolfe A, Moody K, Garcia BA, Thomas DD, Robbins PD, Vijg J, Seluanov A, Suh Y, Gorbunova V. Simon M, et al. Among authors: robbins pd. EMBO J. 2022 Nov 2;41(21):e110393. doi: 10.15252/embj.2021110393. Epub 2022 Oct 10. EMBO J. 2022. PMID: 36215696 Free PMC article.
Nuclear Genomic Instability and Aging.
Niedernhofer LJ, Gurkar AU, Wang Y, Vijg J, Hoeijmakers JHJ, Robbins PD. Niedernhofer LJ, et al. Among authors: robbins pd. Annu Rev Biochem. 2018 Jun 20;87:295-322. doi: 10.1146/annurev-biochem-062917-012239. Annu Rev Biochem. 2018. PMID: 29925262 Review.
Methods to Quantify the NF-κB Pathway During Senescence.
Zhang L, Zhao J, Gurkar A, Niedernhofer LJ, Robbins PD. Zhang L, et al. Among authors: robbins pd. Methods Mol Biol. 2019;1896:231-250. doi: 10.1007/978-1-4939-8931-7_18. Methods Mol Biol. 2019. PMID: 30474851
Signal Transduction, Ageing and Disease.
Zhang L, Yousefzadeh MJ, Suh Y, Niedernhofer LJ, Robbins PD. Zhang L, et al. Among authors: robbins pd. Subcell Biochem. 2019;91:227-247. doi: 10.1007/978-981-13-3681-2_9. Subcell Biochem. 2019. PMID: 30888655 Review.
Development of Clinical Trials to Extend Healthy Lifespan.
Justice JN, Niedernhofer L, Robbins PD, Aroda VR, Espeland MA, Kritchevsky SB, Kuchel GA, Barzilai N. Justice JN, et al. Among authors: robbins pd. Cardiovasc Endocrinol Metab. 2018 Dec;7(4):80-83. doi: 10.1097/XCE.0000000000000159. Cardiovasc Endocrinol Metab. 2018. PMID: 30906924 Free PMC article.
Creating the Next Generation of Translational Geroscientists.
Newman JC, Sokoloski JL, Robbins PD, Niedernhofer LJ, Reed MJ, Wei J, Austad SN, Barzilai N, Cohen HJ, Kuchel GA, Kirkland JL, Pignolo RJ. Newman JC, et al. Among authors: robbins pd. J Am Geriatr Soc. 2019 Sep;67(9):1934-1939. doi: 10.1111/jgs.16055. Epub 2019 Jul 9. J Am Geriatr Soc. 2019. PMID: 31287934 Free PMC article.
Genetics of extreme human longevity to guide drug discovery for healthy ageing.
Zhang ZD, Milman S, Lin JR, Wierbowski S, Yu H, Barzilai N, Gorbunova V, Ladiges WC, Niedernhofer LJ, Suh Y, Robbins PD, Vijg J. Zhang ZD, et al. Among authors: robbins pd. Nat Metab. 2020 Aug;2(8):663-672. doi: 10.1038/s42255-020-0247-0. Epub 2020 Jul 27. Nat Metab. 2020. PMID: 32719537 Free PMC article. Review.
Genetic signature of human longevity in PKC and NF-κB signaling.
Ryu S, Han J, Norden-Krichmar TM, Zhang Q, Lee S, Zhang Z, Atzmon G, Niedernhofer LJ, Robbins PD, Barzilai N, Schork NJ, Suh Y. Ryu S, et al. Among authors: robbins pd. Aging Cell. 2021 Jul;20(7):e13362. doi: 10.1111/acel.13362. Epub 2021 Jul 1. Aging Cell. 2021. PMID: 34197020 Free PMC article.
Recent advances in the discovery of senolytics.
Zhang L, Pitcher LE, Prahalad V, Niedernhofer LJ, Robbins PD. Zhang L, et al. Among authors: robbins pd. Mech Ageing Dev. 2021 Dec;200:111587. doi: 10.1016/j.mad.2021.111587. Epub 2021 Oct 14. Mech Ageing Dev. 2021. PMID: 34656616 Free PMC article. Review.
526 results