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In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states.
Neagu A, van Genderen E, Escudero I, Verwegen L, Kurek D, Lehmann J, Stel J, Dirks RAM, van Mierlo G, Maas A, Eleveld C, Ge Y, den Dekker AT, Brouwer RWW, van IJcken WFJ, Modic M, Drukker M, Jansen JH, Rivron NC, Baart EB, Marks H, Ten Berge D. Neagu A, et al. Among authors: rivron nc. Nat Cell Biol. 2020 May;22(5):534-545. doi: 10.1038/s41556-020-0508-x. Epub 2020 May 4. Nat Cell Biol. 2020. PMID: 32367046
Blastocyst-like structures generated solely from stem cells.
Rivron NC, Frias-Aldeguer J, Vrij EJ, Boisset JC, Korving J, Vivié J, Truckenmüller RK, van Oudenaarden A, van Blitterswijk CA, Geijsen N. Rivron NC, et al. Nature. 2018 May;557(7703):106-111. doi: 10.1038/s41586-018-0051-0. Epub 2018 May 2. Nature. 2018. PMID: 29720634
Human blastoids model blastocyst development and implantation.
Kagawa H, Javali A, Khoei HH, Sommer TM, Sestini G, Novatchkova M, Scholte Op Reimer Y, Castel G, Bruneau A, Maenhoudt N, Lammers J, Loubersac S, Freour T, Vankelecom H, David L, Rivron N. Kagawa H, et al. Nature. 2022 Jan;601(7894):600-605. doi: 10.1038/s41586-021-04267-8. Epub 2021 Dec 2. Nature. 2022. PMID: 34856602 Free PMC article.
Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction.
Zijlmans DW, Talon I, Verhelst S, Bendall A, Van Nerum K, Javali A, Malcolm AA, van Knippenberg SSFA, Biggins L, To SK, Janiszewski A, Admiraal D, Knops R, Corthout N, Balaton BP, Georgolopoulos G, Panda A, Bhanu NV, Collier AJ, Fabian C, Allsop RN, Chappell J, Pham TXA, Oberhuemer M, Ertekin C, Vanheer L, Athanasouli P, Lluis F, Deforce D, Jansen JH, Garcia BA, Vermeulen M, Rivron N, Dhaenens M, Marks H, Rugg-Gunn PJ, Pasque V. Zijlmans DW, et al. Nat Cell Biol. 2022 Jun;24(6):858-871. doi: 10.1038/s41556-022-00932-w. Epub 2022 Jun 13. Nat Cell Biol. 2022. PMID: 35697783 Free PMC article.
Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero.
Seong J, Frias-Aldeguer J, Holzmann V, Kagawa H, Sestini G, Heidari Khoei H, Scholte Op Reimer Y, Kip M, Pradhan SJ, Verwegen L, Vivié J, Li L, Alemany A, Korving J, Darmis F, van Oudenaarden A, Ten Berge D, Geijsen N, Rivron NC. Seong J, et al. Among authors: rivron nc. Cell Stem Cell. 2022 Jul 7;29(7):1102-1118.e8. doi: 10.1016/j.stem.2022.06.002. Cell Stem Cell. 2022. PMID: 35803228 Free article.
Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells.
Pham TXA, Panda A, Kagawa H, To SK, Ertekin C, Georgolopoulos G, van Knippenberg SSFA, Allsop RN, Bruneau A, Chui JS, Vanheer L, Janiszewski A, Chappell J, Oberhuemer M, Tchinda RS, Talon I, Khodeer S, Rossant J, Lluis F, David L, Rivron N, Balaton BP, Pasque V. Pham TXA, et al. Cell Stem Cell. 2022 Sep 1;29(9):1346-1365.e10. doi: 10.1016/j.stem.2022.08.001. Cell Stem Cell. 2022. PMID: 36055191 Free PMC article.
Hypoblast from human pluripotent stem cells regulates epiblast development.
Okubo T, Rivron N, Kabata M, Masaki H, Kishimoto K, Semi K, Nakajima-Koyama M, Kunitomi H, Kaswandy B, Sato H, Nakauchi H, Woltjen K, Saitou M, Sasaki E, Yamamoto T, Takashima Y. Okubo T, et al. Nature. 2024 Feb;626(7998):357-366. doi: 10.1038/s41586-023-06871-2. Epub 2023 Dec 5. Nature. 2024. PMID: 38052228 Free PMC article.
Induction of Human Trophoblast Stem Cells from Somatic Cells and Pluripotent Stem Cells.
Castel G, Meistermann D, Bretin B, Firmin J, Blin J, Loubersac S, Bruneau A, Chevolleau S, Kilens S, Chariau C, Gaignerie A, Francheteau Q, Kagawa H, Charpentier E, Flippe L, François-Campion V, Haider S, Dietrich B, Knöfler M, Arima T, Bourdon J, Rivron N, Masson D, Fournier T, Okae H, Fréour T, David L. Castel G, et al. Cell Rep. 2020 Nov 24;33(8):108419. doi: 10.1016/j.celrep.2020.108419. Cell Rep. 2020. PMID: 33238118 Free article.
43 results