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In vitro to in vivo extrapolation for high throughput prioritization and decision making.
Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer KLR, Casey WM, Choksi N, Ferguson SS, Fraczkiewicz G, Jarabek AM, Ke A, Lumen A, Lynn SG, Paini A, Price PS, Ring C, Simon TW, Sipes NS, Sprankle CS, Strickland J, Troutman J, Wetmore BA, Kleinstreuer NC. Bell SM, et al. Among authors: ring c. Toxicol In Vitro. 2018 Mar;47:213-227. doi: 10.1016/j.tiv.2017.11.016. Epub 2017 Dec 5. Toxicol In Vitro. 2018. PMID: 29203341 Free PMC article. Review.
Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics.
Wambaugh JF, Hughes MF, Ring CL, MacMillan DK, Ford J, Fennell TR, Black SR, Snyder RW, Sipes NS, Wetmore BA, Westerhout J, Setzer RW, Pearce RG, Simmons JE, Thomas RS. Wambaugh JF, et al. Toxicol Sci. 2018 May 1;163(1):152-169. doi: 10.1093/toxsci/kfy020. Toxicol Sci. 2018. PMID: 29385628 Free PMC article.
Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization.
Wambaugh JF, Wetmore BA, Ring CL, Nicolas CI, Pearce RG, Honda GS, Dinallo R, Angus D, Gilbert J, Sierra T, Badrinarayanan A, Snodgrass B, Brockman A, Strock C, Setzer RW, Thomas RS. Wambaugh JF, et al. Among authors: ring cl. Toxicol Sci. 2019 Dec 1;172(2):235-251. doi: 10.1093/toxsci/kfz205. Toxicol Sci. 2019. PMID: 31532498 Free PMC article.
High-throughput PBTK models for in vitro to in vivo extrapolation.
Breen M, Ring CL, Kreutz A, Goldsmith MR, Wambaugh JF. Breen M, et al. Expert Opin Drug Metab Toxicol. 2021 Aug;17(8):903-921. doi: 10.1080/17425255.2021.1935867. Epub 2021 Jun 15. Expert Opin Drug Metab Toxicol. 2021. PMID: 34056988 Free PMC article. Review.
361 results