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Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS.
Zinngrebe J, Moepps B, Monecke T, Gierschik P, Schlichtig F, Barth TFE, Strauß G, Boldrin E, Posovszky C, Schulz A, Beringer O, Rieser E, Jacobsen EM, Lorenz MR, Schwarz K, Pannicke U, Walczak H, Niessing D, Schuetz C, Fischer-Posovszky P, Debatin KM. Zinngrebe J, et al. Among authors: rieser e. EMBO Mol Med. 2022 Mar 7;14(3):e14901. doi: 10.15252/emmm.202114901. Epub 2022 Feb 16. EMBO Mol Med. 2022. PMID: 35170849 Free PMC article.
--LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation.
Zinngrebe J, Rieser E, Taraborrelli L, Peltzer N, Hartwig T, Ren H, Kovács I, Endres C, Draber P, Darding M, von Karstedt S, Lemke J, Dome B, Bergmann M, Ferguson BJ, Walczak H. Zinngrebe J, et al. Among authors: rieser e. J Exp Med. 2016 Nov 14;213(12):2671-2689. doi: 10.1084/jem.20160041. Epub 2016 Oct 24. J Exp Med. 2016. PMID: 27810922 Free PMC article.
Linear ubiquitination at a glance.
Spit M, Rieser E, Walczak H. Spit M, et al. Among authors: rieser e. J Cell Sci. 2019 Jan 18;132(2):jcs208512. doi: 10.1242/jcs.208512. J Cell Sci. 2019. PMID: 30659056 Review.
LUBAC is required for RIG-I sensing of RNA viruses.
Teague HC, Lefevre C, Rieser E, Wolfram L, de Miguel D, Patricio de Oliveira D, Oliveira M, Mansur DS, Irigoyen N, Walczak H, Ferguson BJ. Teague HC, et al. Among authors: rieser e. Cell Death Differ. 2024 Jan;31(1):28-39. doi: 10.1038/s41418-023-01233-x. Epub 2023 Nov 24. Cell Death Differ. 2024. PMID: 38001254 Free PMC article.
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.
Haas TL, Emmerich CH, Gerlach B, Schmukle AC, Cordier SM, Rieser E, Feltham R, Vince J, Warnken U, Wenger T, Koschny R, Komander D, Silke J, Walczak H. Haas TL, et al. Among authors: rieser e. Mol Cell. 2009 Dec 11;36(5):831-44. doi: 10.1016/j.molcel.2009.10.013. Mol Cell. 2009. PMID: 20005846 Free article.
26 results