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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2006 1
2007 1
2008 4
2009 5
2010 6
2011 4
2012 7
2013 6
2014 8
2015 8
2016 7
2017 11
2018 18
2019 16
2020 23
2021 19
2022 23
2023 15
2024 9

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176 results

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Page 1
A conserved complex lipid signature marks human muscle aging and responds to short-term exercise.
Janssens GE, Molenaars M, Herzog K, Grevendonk L, Remie CME, Vervaart MAT, Elfrink HL, Wever EJM, Schomakers BV, Denis SW, Waterham HR, Pras-Raves ML, van Weeghel M, van Kampen AHC, Tammaro A, Butter LM, van der Rijt S, Florquin S, Jongejan A, Moerland PD, Hoeks J, Schrauwen P, Vaz FM, Houtkooper RH. Janssens GE, et al. Among authors: houtkooper rh. Nat Aging. 2024 Apr 12. doi: 10.1038/s43587-024-00595-2. Online ahead of print. Nat Aging. 2024. PMID: 38609524
CIAO1 and MMS19 deficiency: A lethal neurodegenerative phenotype caused by cytosolic Fe-S cluster protein assembly disorders.
van Karnebeek CDM, Tarailo-Graovac M, Leen R, Meinsma R, Correard S, Jansen-Meijer J, Prykhozhij SV, Pena IA, Ban K, Schock S, Saxena V, Pras-Raves ML, Drögemöller BI, Grootemaat AE, van der Wel NN, Dobritzsch D, Roseboom W, Schomakers BV, Jaspers YRJ, Zoetekouw L, Roelofsen J, Ferreira CR, van der Lee R, Ross CJ, Kochan J, McIntyre RL, van Klinken JB, van Weeghel M, Kramer G, Weschke B, Labrune P, Willemsen MA, Riva D, Garavaglia B, Moeschler JB, Filiano JJ, Ekker M, Berman JN, Dyment D, Vaz FM, Wassermann WW, Houtkooper RH, van Kuilenburg ABP. van Karnebeek CDM, et al. Among authors: houtkooper rh. Genet Med. 2024 Feb 24;26(6):101104. doi: 10.1016/j.gim.2024.101104. Online ahead of print. Genet Med. 2024. PMID: 38411040 Free article.
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells.
Liang Z, Ralph-Epps T, Schmidtke MW, Lazcano P, Denis SW, Balážová M, Chakkour M, Hazime S, Ren M, Schlame M, Houtkooper RH, Greenberg ML. Liang Z, et al. Among authors: houtkooper rh. bioRxiv [Preprint]. 2024 Feb 4:2024.02.03.578755. doi: 10.1101/2024.02.03.578755. bioRxiv. 2024. PMID: 38352304 Free PMC article. Preprint.
High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan.
Gao AW, Alam GE, Zhu Y, Li W, Katsyuba E, Sulc J, Li TY, Li X, Overmyer KA, Lalou A, Mouchiroud L, Sleiman MB, Cornaglia M, Morel JD, Houtkooper RH, Coon JJ, Auwerx J. Gao AW, et al. Among authors: houtkooper rh. bioRxiv [Preprint]. 2024 Jan 16:2024.01.15.575638. doi: 10.1101/2024.01.15.575638. bioRxiv. 2024. PMID: 38293129 Free PMC article. Preprint.
Doxycycline induces mitochondrial dysfunction in aortic smooth muscle cells.
Yap C, Wanga S, Wüst RCI, van Os BW, Pijls MME, Keijzer S, van Zanten E, Koolbergen DR, Driessen AHG, Balm R, Yeung KK, de Vries CJM, Houtkooper RH, Lindeman JHN, de Waard V. Yap C, et al. Among authors: houtkooper rh. Vascul Pharmacol. 2024 Mar;154:107279. doi: 10.1016/j.vph.2024.107279. Epub 2024 Jan 23. Vascul Pharmacol. 2024. PMID: 38272196 Free article.
HDAC1/2 inhibitor therapy improves multiple organ systems in aged mice.
Tammaro A, Daniels EG, Hu IM, 't Hart KC, Reid K, Juni RP, Butter LM, Vasam G, Kamble R, Jongejan A, Aviv RI, Roelofs JJTH, Aronica E, Boon RA, Menzies KJ, Houtkooper RH, Janssens GE. Tammaro A, et al. Among authors: houtkooper rh. iScience. 2023 Dec 12;27(1):108681. doi: 10.1016/j.isci.2023.108681. eCollection 2024 Jan 19. iScience. 2023. PMID: 38269100 Free PMC article.
Ophthalmic acid is a glutathione regulating tripeptide.
Schomakers BV, Jillings SL, van Weeghel M, Vaz FM, Salomons GS, Janssens GE, Houtkooper RH. Schomakers BV, et al. Among authors: houtkooper rh. FEBS J. 2024 Jan 20. doi: 10.1111/febs.17061. Online ahead of print. FEBS J. 2024. PMID: 38245827
Vision on gyrate atrophy: why treat the eye?
Bergen AA, Buijs MJ, Ten Asbroek AL, Balfoort BM, Boon CJ; Dutch GACR “Bird’s Eye View” Consortium; Brands MM, Wanders RJ, van Karnebeek CD, Houtkooper RH. Bergen AA, et al. Among authors: houtkooper rh. EMBO Mol Med. 2024 Jan;16(1):4-7. doi: 10.1038/s44321-023-00001-1. Epub 2023 Dec 14. EMBO Mol Med. 2024. PMID: 38177529 Free PMC article.
Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death.
Léopold V, Chouchane O, Butler JM, Schuurman AR, Michels EHA, de Brabander J, Schomakers BV, van Weeghel M, Picavet-Havik DI, Grootemaat AE, Douma RA, Reijnders TDY, Klarenbeek AM, Appelman B; Amsterdam University Medical Center COVID-19 Biobank Study Groupd.vandebeek@amsterdamumc.nl; Wiersinga WJ, van der Wel NN, den Dunnen J, Houtkooper RH, Van't Veer C, van der Poll T; Amsterdam University Medical Center COVID-19 Biobank Study Group. Léopold V, et al. Among authors: houtkooper rh. Res Pract Thromb Haemost. 2023 Sep 28;7(7):102213. doi: 10.1016/j.rpth.2023.102213. eCollection 2023 Oct. Res Pract Thromb Haemost. 2023. PMID: 38077825 Free PMC article.
176 results