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Cas9-expressing chickens and pigs as resources for genome editing in livestock.
Rieblinger B, Sid H, Duda D, Bozoglu T, Klinger R, Schlickenrieder A, Lengyel K, Flisikowski K, Flisikowska T, Simm N, Grodziecki A, Perleberg C, Bähr A, Carrier L, Kurome M, Zakhartchenko V, Kessler B, Wolf E, Kettler L, Luksch H, Hagag IT, Wise D, Kaufman J, Kaufer BB, Kupatt C, Schnieke A, Schusser B. Rieblinger B, et al. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2022562118. doi: 10.1073/pnas.2022562118. Proc Natl Acad Sci U S A. 2021. PMID: 33658378 Free PMC article.
Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing.
Fischer K, Kraner-Scheiber S, Petersen B, Rieblinger B, Buermann A, Flisikowska T, Flisikowski K, Christan S, Edlinger M, Baars W, Kurome M, Zakhartchenko V, Kessler B, Plotzki E, Szczerbal I, Switonski M, Denner J, Wolf E, Schwinzer R, Niemann H, Kind A, Schnieke A. Fischer K, et al. Among authors: rieblinger b. Sci Rep. 2016 Jun 29;6:29081. doi: 10.1038/srep29081. Sci Rep. 2016. PMID: 27353424 Free PMC article.
Strong xenoprotective function by single-copy transgenes placed sequentially at a permissive locus.
Rieblinger B, Fischer K, Kind A, Saller BS, Baars W, Schuster M, Wolf-van Buerck L, Schäffler A, Flisikowska T, Kurome M, Zakhartchenko V, Kessler B, Flisikowski K, Wolf E, Seissler J, Schwinzer R, Schnieke A. Rieblinger B, et al. Xenotransplantation. 2018 Mar;25(2):e12382. doi: 10.1111/xen.12382. Epub 2018 Jan 23. Xenotransplantation. 2018. PMID: 29359453
Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2.
Fischer K, Rieblinger B, Hein R, Sfriso R, Zuber J, Fischer A, Klinger B, Liang W, Flisikowski K, Kurome M, Zakhartchenko V, Kessler B, Wolf E, Rieben R, Schwinzer R, Kind A, Schnieke A. Fischer K, et al. Among authors: rieblinger b. Xenotransplantation. 2020 Jan;27(1):e12560. doi: 10.1111/xen.12560. Epub 2019 Oct 8. Xenotransplantation. 2020. PMID: 31591751 Free article.
Porcine model elucidates function of p53 isoform in carcinogenesis and reveals novel circTP53 RNA.
Niu G, Hellmuth I, Flisikowska T, Pausch H, Rieblinger B, Carrapeiro A, Schade B, Böhm B, Kappe E, Fischer K, Klinger B, Steiger K, Burgkart R, Bourdon JC, Saur D, Kind A, Schnieke A, Flisikowski K. Niu G, et al. Among authors: rieblinger b. Oncogene. 2021 Mar;40(10):1896-1908. doi: 10.1038/s41388-021-01686-9. Epub 2021 Feb 18. Oncogene. 2021. PMID: 33603167 Free PMC article.
Maternal placenta modulates a deleterious fetal mutation.
Xu H, Pausch H, Venhoranta H, Rutkowska K, Wurmser C, Rieblinger B, Flisikowska T, Frishman D, Zwierzchowski L, Fries R, Andersson M, Kind A, Schnieke A, Flisikowski K. Xu H, et al. Among authors: rieblinger b. Biol Reprod. 2017 Aug 1;97(2):249-257. doi: 10.1093/biolre/iox064. Biol Reprod. 2017. PMID: 28679164
Genome Editing in Pigs.
Preisinger D, Winogrodzki T, Klinger B, Schnieke A, Rieblinger B. Preisinger D, et al. Among authors: rieblinger b. Methods Mol Biol. 2023;2631:393-417. doi: 10.1007/978-1-0716-2990-1_19. Methods Mol Biol. 2023. PMID: 36995680