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Induction of cardiac FGF23/FGFR4 expression is associated with left ventricular hypertrophy in patients with chronic kidney disease.
Leifheit-Nestler M, Große Siemer R, Flasbart K, Richter B, Kirchhoff F, Ziegler WH, Klintschar M, Becker JU, Erbersdobler A, Aufricht C, Seeman T, Fischer DC, Faul C, Haffner D. Leifheit-Nestler M, et al. Among authors: richter b. Nephrol Dial Transplant. 2016 Jul;31(7):1088-99. doi: 10.1093/ndt/gfv421. Epub 2015 Dec 17. Nephrol Dial Transplant. 2016. PMID: 26681731 Free PMC article.
Fibroblast growth factor 23 is induced by an activated renin-angiotensin-aldosterone system in cardiac myocytes and promotes the pro-fibrotic crosstalk between cardiac myocytes and fibroblasts.
Leifheit-Nestler M, Kirchhoff F, Nespor J, Richter B, Soetje B, Klintschar M, Heineke J, Haffner D. Leifheit-Nestler M, et al. Among authors: richter b. Nephrol Dial Transplant. 2018 Oct 1;33(10):1722-1734. doi: 10.1093/ndt/gfy006. Nephrol Dial Transplant. 2018. PMID: 29425341
Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy.
Grabner A, Amaral AP, Schramm K, Singh S, Sloan A, Yanucil C, Li J, Shehadeh LA, Hare JM, David V, Martin A, Fornoni A, Di Marco GS, Kentrup D, Reuter S, Mayer AB, Pavenstädt H, Stypmann J, Kuhn C, Hille S, Frey N, Leifheit-Nestler M, Richter B, Haffner D, Abraham R, Bange J, Sperl B, Ullrich A, Brand M, Wolf M, Faul C. Grabner A, et al. Among authors: richter b. Cell Metab. 2015 Dec 1;22(6):1020-32. doi: 10.1016/j.cmet.2015.09.002. Epub 2015 Oct 1. Cell Metab. 2015. PMID: 26437603 Free PMC article.
Cardiac Fibroblast Growth Factor 23 Excess Does Not Induce Left Ventricular Hypertrophy in Healthy Mice.
Leifheit-Nestler M, Wagner MA, Richter B, Piepert C, Eitner F, Böckmann I, Vogt I, Grund A, Hille SS, Foinquinos A, Zimmer K, Thum T, Müller OJ, Haffner D. Leifheit-Nestler M, et al. Among authors: richter b. Front Cell Dev Biol. 2021 Oct 28;9:745892. doi: 10.3389/fcell.2021.745892. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34778257 Free PMC article.
Phosphate Is a Cardiovascular Toxin.
Leifheit-Nestler M, Vogt I, Haffner D, Richter B. Leifheit-Nestler M, et al. Among authors: richter b. Adv Exp Med Biol. 2022;1362:107-134. doi: 10.1007/978-3-030-91623-7_11. Adv Exp Med Biol. 2022. PMID: 35288877 Review.
762 results