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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 2
2007 4
2008 2
2011 1
2012 2
2013 2
2014 4
2015 3
2016 2
2017 2
2018 5
2019 3
2020 4
2021 4
2022 4
2023 4
2024 0

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45 results

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Page 1
Short-course combination treatment for experimental chronic Chagas disease.
González S, Wall RJ, Thomas J, Braillard S, Brunori G, Camino Díaz I, Cantizani J, Carvalho S, Castañeda Casado P, Chatelain E, Cotillo I, Fiandor JM, Francisco AF, Grimsditch D, Keenan M, Kelly JM, Kessler A, Luise C, Lyon JJ, MacLean L, Marco M, Martin JJ, Martinez Martinez MS, Paterson C, Read KD, Santos-Villarejo A, Zuccotto F, Wyllie S, Miles TJ, De Rycker M. González S, et al. Among authors: wall rj. Sci Transl Med. 2023 Dec 13;15(726):eadg8105. doi: 10.1126/scitranslmed.adg8105. Epub 2023 Dec 13. Sci Transl Med. 2023. PMID: 38091410 Free PMC article.
DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc1.
Braillard S, Keenan M, Breese KJ, Heppell J, Abbott M, Islam R, Shackleford DM, Katneni K, Crighton E, Chen G, Patil R, Lee G, White KL, Carvalho S, Wall RJ, Chemi G, Zuccotto F, González S, Marco M, Deakyne J, Standing D, Brunori G, Lyon JJ, Castañeda-Casado P, Camino I, Martinez Martinez MS, Zulfiqar B, Avery VM, Feijens PB, Van Pelt N, Matheeussen A, Hendrickx S, Maes L, Caljon G, Yardley V, Wyllie S, Charman SA, Chatelain E. Braillard S, et al. Among authors: wall rj. Sci Transl Med. 2023 Dec 13;15(726):eadh9902. doi: 10.1126/scitranslmed.adh9902. Epub 2023 Dec 13. Sci Transl Med. 2023. PMID: 38091406 Free PMC article.
Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues.
Cleghorn LAT, Wall RJ, Albrecht S, MacGowan SA, Norval S, De Rycker M, Woodland A, Spinks D, Thompson S, Patterson S, Corpas Lopez V, Dey G, Collie IT, Hallyburton I, Kime R, Simeons FRC, Stojanovski L, Frearson JA, Wyatt PG, Read KD, Gilbert IH, Wyllie S. Cleghorn LAT, et al. Among authors: wall rj. J Med Chem. 2023 Jul 13;66(13):8896-8916. doi: 10.1021/acs.jmedchem.3c00509. Epub 2023 Jun 21. J Med Chem. 2023. PMID: 37343180 Free PMC article.
Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase.
Milne R, Wiedemar N, Corpas-Lopez V, Moynihan E, Wall RJ, Dawson A, Robinson DA, Shepherd SM, Smith RJ, Hallyburton I, Post JM, Dowers K, Torrie LS, Gilbert IH, Baragaña B, Patterson S, Wyllie S. Milne R, et al. Among authors: wall rj. ACS Infect Dis. 2022 Sep 9;8(9):1962-1974. doi: 10.1021/acsinfecdis.2c00364. Epub 2022 Aug 29. ACS Infect Dis. 2022. PMID: 36037410 Free PMC article.
Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis.
Smith A, Wall RJ, Patterson S, Rowan T, Rico Vidal E, Stojanovski L, Huggett M, Hampton SE, Thomas MG, Corpas Lopez V, Gillingwater K, Duke J, Napier G, Peter R, Vitouley HS, Harrison JR, Milne R, Jeacock L, Baker N, Davis SH, Simeons F, Riley J, Horn D, Brun R, Zuccotto F, Witty MJ, Wyllie S, Read KD, Gilbert IH. Smith A, et al. Among authors: wall rj. J Med Chem. 2022 Apr 14;65(7):5606-5624. doi: 10.1021/acs.jmedchem.1c02104. Epub 2022 Mar 18. J Med Chem. 2022. PMID: 35303411 Free PMC article.
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis.
Mowbray CE, Braillard S, Glossop PA, Whitlock GA, Jacobs RT, Speake J, Pandi B, Nare B, Maes L, Yardley V, Freund Y, Wall RJ, Carvalho S, Bello D, Van den Kerkhof M, Caljon G, Gilbert IH, Corpas-Lopez V, Lukac I, Patterson S, Zuccotto F, Wyllie S. Mowbray CE, et al. Among authors: wall rj. J Med Chem. 2021 Nov 11;64(21):16159-16176. doi: 10.1021/acs.jmedchem.1c01437. Epub 2021 Oct 28. J Med Chem. 2021. PMID: 34711050 Free PMC article.
Identification of a Proteasome-Targeting Arylsulfonamide with Potential for the Treatment of Chagas' Disease.
Lima ML, Tulloch LB, Corpas-Lopez V, Carvalho S, Wall RJ, Milne R, Rico E, Patterson S, Gilbert IH, Moniz S, MacLean L, Torrie LS, Morgillo C, Horn D, Zuccotto F, Wyllie S. Lima ML, et al. Among authors: wall rj. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0153521. doi: 10.1128/AAC.01535-21. Epub 2021 Oct 4. Antimicrob Agents Chemother. 2022. PMID: 34606338 Free PMC article.
Identification of Resistance Determinants for a Promising Antileishmanial Oxaborole Series.
Van den Kerkhof M, Leprohon P, Mabille D, Hendrickx S, Tulloch LB, Wall RJ, Wyllie S, Chatelain E, Mowbray CE, Braillard S, Ouellette M, Maes L, Caljon G. Van den Kerkhof M, et al. Among authors: wall rj. Microorganisms. 2021 Jun 29;9(7):1408. doi: 10.3390/microorganisms9071408. Microorganisms. 2021. PMID: 34210040 Free PMC article.
45 results