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Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis.
Schepers M, Paes D, Tiane A, Rombaut B, Piccart E, van Veggel L, Gervois P, Wolfs E, Lambrichts I, Brullo C, Bruno O, Fedele E, Ricciarelli R, Ffrench-Constant C, Bechler ME, van Schaik P, Baron W, Lefevere E, Wasner K, Grünewald A, Verfaillie C, Baeten P, Broux B, Wieringa P, Hellings N, Prickaerts J, Vanmierlo T. Schepers M, et al. Among authors: ricciarelli r. Brain Behav Immun. 2023 Mar;109:1-22. doi: 10.1016/j.bbi.2022.12.020. Epub 2022 Dec 28. Brain Behav Immun. 2023. PMID: 36584795 Free article.
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology.
Paes D, Schepers M, Willems E, Rombaut B, Tiane A, Solomina Y, Tibbo A, Blair C, Kyurkchieva E, Baillie GS, Ricciarelli R, Brullo C, Fedele E, Bruno O, van den Hove D, Vanmierlo T, Prickaerts J. Paes D, et al. Among authors: ricciarelli r. Cell Mol Life Sci. 2023 Jun 12;80(7):178. doi: 10.1007/s00018-023-04804-w. Cell Mol Life Sci. 2023. PMID: 37306762 Free PMC article.
Amelioration of functional and histopathological consequences after spinal cord injury through phosphodiesterase 4D (PDE4D) inhibition.
Schepers M, Hendrix S, Mussen F, van Breedam E, Ponsaerts P, Lemmens S, Hellings N, Ricciarelli R, Fedele E, Bruno O, Brullo C, Prickaerts J, Van Broeckhoven J, Vanmierlo T. Schepers M, et al. Among authors: ricciarelli r. Neurotherapeutics. 2024 May 16:e00372. doi: 10.1016/j.neurot.2024.e00372. Online ahead of print. Neurotherapeutics. 2024. PMID: 38760316 Free article.
Tau, tau kinases, and tauopathies: An updated overview.
Montalto G, Ricciarelli R. Montalto G, et al. Among authors: ricciarelli r. Biofactors. 2023 May-Jun;49(3):502-511. doi: 10.1002/biof.1930. Epub 2023 Jan 23. Biofactors. 2023. PMID: 36688478 Review.
A New Bistable Switch Model of Alzheimer's Disease Pathogenesis.
Burlando B, Losacco S, Villa V, Fedele E, Ricciarelli R. Burlando B, et al. Among authors: ricciarelli r. Int J Mol Sci. 2022 Jun 25;23(13):7061. doi: 10.3390/ijms23137061. Int J Mol Sci. 2022. PMID: 35806088 Free PMC article.
Oxidized LDLs as Signaling Molecules.
Zingg JM, Vlad A, Ricciarelli R. Zingg JM, et al. Among authors: ricciarelli r. Antioxidants (Basel). 2021 Jul 26;10(8):1184. doi: 10.3390/antiox10081184. Antioxidants (Basel). 2021. PMID: 34439432 Free PMC article. Review.
83 results