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NSAIDs: Old Drugs Reveal New Anticancer Targets.
Piazza GA, Keeton AB, Tinsley HN, Whitt JD, Gary BD, Mathew B, Singh R, Grizzle WE, Reynolds RC. Piazza GA, et al. Among authors: reynolds rc. Pharmaceuticals (Basel). 2010 May 25;3(5):1652-1667. doi: 10.3390/ph3051652. Pharmaceuticals (Basel). 2010. PMID: 27713322 Free PMC article. Review.
A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity.
Piazza GA, Keeton AB, Tinsley HN, Gary BD, Whitt JD, Mathew B, Thaiparambil J, Coward L, Gorman G, Li Y, Sani B, Hobrath JV, Maxuitenko YY, Reynolds RC. Piazza GA, et al. Among authors: reynolds rc. Cancer Prev Res (Phila). 2009 Jun;2(6):572-80. doi: 10.1158/1940-6207.CAPR-09-0001. Epub 2009 May 26. Cancer Prev Res (Phila). 2009. PMID: 19470791 Free PMC article.
A novel quinoline derivative that inhibits mycobacterial FtsZ.
Mathew B, Ross L, Reynolds RC. Mathew B, et al. Among authors: reynolds rc. Tuberculosis (Edinb). 2013 Jul;93(4):398-400. doi: 10.1016/j.tube.2013.04.002. Epub 2013 May 4. Tuberculosis (Edinb). 2013. PMID: 23647650 Free PMC article.
Oxazole and thiazole analogs of sulindac for cancer prevention.
Mathew B, Hobrath JV, Connelly MC, Guy RK, Reynolds RC. Mathew B, et al. Among authors: reynolds rc. Future Med Chem. 2018 Apr 1;10(7):743-753. doi: 10.4155/fmc-2017-0182. Epub 2018 Apr 19. Future Med Chem. 2018. PMID: 29671617 Free PMC article.
Diverse amide analogs of sulindac for cancer treatment and prevention.
Mathew B, Hobrath JV, Connelly MC, Kiplin Guy R, Reynolds RC. Mathew B, et al. Among authors: reynolds rc. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4614-4621. doi: 10.1016/j.bmcl.2017.09.022. Epub 2017 Sep 13. Bioorg Med Chem Lett. 2017. PMID: 28935266 Free PMC article.
Amine Containing Analogs of Sulindac for Cancer Prevention.
Mathew B, Hobrath JV, Connelly MC, Guy RK, Reynolds RC. Mathew B, et al. Among authors: reynolds rc. Open Med Chem J. 2018 Jan 31;12:1-12. doi: 10.2174/1874104501812010001. eCollection 2018. Open Med Chem J. 2018. PMID: 29492166 Free PMC article.
292 results