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Discovery of Potent Tetrazole Free Fatty Acid Receptor 2 Antagonists.
Valentini A, Schultz-Knudsen K, Højgaard Hansen A, Tsakoumagkou A, Jenkins L, Christensen HB, Manandhar A, Milligan G, Ulven T, Rexen Ulven E. Valentini A, et al. Among authors: rexen ulven e. J Med Chem. 2023 May 11;66(9):6105-6121. doi: 10.1021/acs.jmedchem.2c01935. Epub 2023 May 2. J Med Chem. 2023. PMID: 37129317 Free PMC article.
Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets.
Lorza-Gil E, Kaiser G, Carlein C, Hoffmann MDA, König GM, Haug S, Prates Roma L, Rexen Ulven E, Ulven T, Kostenis E, Birkenfeld AL, Häring HU, Ullrich S, Gerst F. Lorza-Gil E, et al. Among authors: rexen ulven e. Diabetologia. 2023 Aug;66(8):1501-1515. doi: 10.1007/s00125-023-05932-5. Epub 2023 May 23. Diabetologia. 2023. PMID: 37217659 Free PMC article.
Ligand entry pathways control the chemical space recognized by GPR183.
Kjær VMS, Stępniewski TM, Medel-Lacruz B, Reinmuth L, Ciba M, Rexen Ulven E, Bonomi M, Selent J, Rosenkilde MM. Kjær VMS, et al. Among authors: rexen ulven e. Chem Sci. 2023 Sep 25;14(39):10671-10683. doi: 10.1039/d2sc05962b. eCollection 2023 Oct 11. Chem Sci. 2023. PMID: 37829039 Free PMC article.
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