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Page 1
Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2.
Israeli M, Finkel Y, Yahalom-Ronen Y, Paran N, Chitlaru T, Israeli O, Cohen-Gihon I, Aftalion M, Falach R, Rotem S, Elia U, Nemet I, Kliker L, Mandelboim M, Beth-Din A, Israely T, Cohen O, Stern-Ginossar N, Bercovich-Kinori A. Israeli M, et al. Among authors: falach r. Nat Commun. 2022 Apr 25;13(1):2237. doi: 10.1038/s41467-022-29896-z. Nat Commun. 2022. PMID: 35469023 Free PMC article.
Prolonged Protective Immunity Induced by Mild SARS-CoV-2 Infection of K18-hACE2 Mice.
Bar-On L, Aftalion M, Makdasi E, Gur D, Alcalay R, Cohen H, Beth-Din A, Rosenfeld R, Achdout H, Bar-Haim E, Falach R, Chitlaru T, Cohen O. Bar-On L, et al. Among authors: falach r. Vaccines (Basel). 2022 Apr 14;10(4):613. doi: 10.3390/vaccines10040613. Vaccines (Basel). 2022. PMID: 35455362 Free PMC article.
Implementation of Adenovirus-Mediated Pulmonary Expression of Human ACE2 in HLA Transgenic Mice Enables Establishment of a COVID-19 Murine Model for Assessment of Immune Responses to SARS-CoV-2 Infection.
Chitlaru T, Bar-Haim E, Bar-On L, Rotem S, Cohen H, Elia U, Gur D, Aftalion M, Alkalay R, Makdasi E, Evgy Y, Falach R, Israeli M, Bercovich-Kinori A, Achdout H, Yahalom-Ronen Y, Rosenfeld R, Cohen O. Chitlaru T, et al. Among authors: falach r. Pathogens. 2021 Jul 26;10(8):940. doi: 10.3390/pathogens10080940. Pathogens. 2021. PMID: 34451403 Free PMC article.
Mice with induced pulmonary morbidities display severe lung inflammation and mortality following exposure to SARS-CoV-2.
Falach R, Bar-On L, Lazar S, Kadar T, Mazor O, Aftalion M, Gur D, Evgy Y, Shifman O, Aminov T, Israeli O, Cohen-Gihon I, Zaide G, Gutman H, Vagima Y, Makdasi E, Stein D, Rosenfeld R, Alcalay R, Zahavy E, Levy H, Glinert I, Ben-Shmuel A, Israely T, Melamed S, Politi B, Achdout H, Yitzhaki S, Kronman C, Sabo T. Falach R, et al. JCI Insight. 2021 Jun 22;6(12):e145916. doi: 10.1172/jci.insight.145916. JCI Insight. 2021. PMID: 33974566 Free PMC article.
Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice.
Noy-Porat T, Mechaly A, Levy Y, Makdasi E, Alcalay R, Gur D, Aftalion M, Falach R, Leviatan Ben-Arye S, Lazar S, Zauberman A, Epstein E, Chitlaru T, Weiss S, Achdout H, Edgeworth JD, Kikkeri R, Yu H, Chen X, Yitzhaki S, Shapira SC, Padler-Karavani V, Mazor O, Rosenfeld R. Noy-Porat T, et al. Among authors: falach r. iScience. 2021 May 21;24(5):102479. doi: 10.1016/j.isci.2021.102479. Epub 2021 Apr 26. iScience. 2021. PMID: 33937725 Free PMC article.
Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody.
Rosenfeld R, Noy-Porat T, Mechaly A, Makdasi E, Levy Y, Alcalay R, Falach R, Aftalion M, Epstein E, Gur D, Chitlaru T, Vitner EB, Melamed S, Politi B, Zauberman A, Lazar S, Beth-Din A, Evgy Y, Yitzhaki S, Shapira SC, Israely T, Mazor O. Rosenfeld R, et al. Among authors: falach r. Nat Commun. 2021 Feb 11;12(1):944. doi: 10.1038/s41467-021-21239-8. Nat Commun. 2021. PMID: 33574228 Free PMC article.
25 results