Reto Brun - Search Results

Year	Number of Results
2002	15
2003	18
2004	24
2005	25
2006	29
2007	30
2008	35
2009	45
2010	45
2011	42
2012	24
2013	37
2014	23
2015	15
2016	14
2017	18
2018	11
2019	5
2021	2
2022	1
2023	2
2024	0

1

Key Contributions by the Swiss Tropical and Public Health Institute Towards New and Better Drugs for Tropical Diseases.

Mäser P, Bernhard S, Brun R, Burri C, Gagneux S, Hetzel MW, Kaiser M, Lengeler C, Pluschke G, Reus E, Rottmann M, Utzinger J, Warryn L, Wittlin S, Keiser J. Mäser P, et al. Among authors: brun r. Chimia (Aarau). 2023 Sep 20;77(9):593-602. doi: 10.2533/chimia.2023.593. Chimia (Aarau). 2023. PMID: 38047835 Free article.

2

Investigation of the effect of structure modification of furamidine on the DNA minor groove binding and antiprotozoal activity.

Farahat AA, Kumar A, Wenzler T, Brun R, Paul A, Guo P, Wilson WD, Boykin DW. Farahat AA, et al. Among authors: brun r. Eur J Med Chem. 2023 Apr 5;252:115287. doi: 10.1016/j.ejmech.2023.115287. Epub 2023 Mar 20. Eur J Med Chem. 2023. PMID: 36958267 Free PMC article.

3

Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis.

Smith A, Wall RJ, Patterson S, Rowan T, Rico Vidal E, Stojanovski L, Huggett M, Hampton SE, Thomas MG, Corpas Lopez V, Gillingwater K, Duke J, Napier G, Peter R, Vitouley HS, Harrison JR, Milne R, Jeacock L, Baker N, Davis SH, Simeons F, Riley J, Horn D, Brun R, Zuccotto F, Witty MJ, Wyllie S, Read KD, Gilbert IH. Smith A, et al. Among authors: brun r. J Med Chem. 2022 Apr 14;65(7):5606-5624. doi: 10.1021/acs.jmedchem.1c02104. Epub 2022 Mar 18. J Med Chem. 2022. PMID: 35303411 Free PMC article.

4

New antiparasitic flexible triaryl diamidines, their prodrugs and aza analogues: Synthesis, in vitro and in vivo biological evaluation, and molecular modelling studies.

Arafa RK, Ismail MA, Wenzler T, Brun R, Paul A, Wilson WD, Alakhdar AA, Boykin DW. Arafa RK, et al. Among authors: brun r. Eur J Med Chem. 2021 Oct 15;222:113625. doi: 10.1016/j.ejmech.2021.113625. Epub 2021 Jun 9. Eur J Med Chem. 2021. PMID: 34146914

5

Synthesis, in vitro antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles.

Doganc F, Celik I, Eren G, Kaiser M, Brun R, Goker H. Doganc F, et al. Among authors: brun r. Eur J Med Chem. 2021 Oct 5;221:113545. doi: 10.1016/j.ejmech.2021.113545. Epub 2021 May 24. Eur J Med Chem. 2021. PMID: 34091216

6

A Near-Complete Series of Four Atropisomeric Jozimine A₂-Type Naphthylisoquinoline Dimers with Antiplasmodial and Cytotoxic Activities and Related Alkaloids from Ancistrocladus abbreviatus.

Fayez S, Li J, Feineis D, Aké Assi L, Kaiser M, Brun R, Anany MA, Wajant H, Bringmann G. Fayez S, et al. Among authors: brun r. J Nat Prod. 2019 Nov 22;82(11):3033-3046. doi: 10.1021/acs.jnatprod.9b00589. Epub 2019 Oct 23. J Nat Prod. 2019. PMID: 31642313

7

Ealamines A-H, a Series of Naphthylisoquinolines with the Rare 7,8'-Coupling Site, from the Congolese Liana Ancistrocladus ealaensis, Targeting Pancreatic Cancer Cells.

Tshitenge DT, Bruhn T, Feineis D, Schmidt D, Mudogo V, Kaiser M, Brun R, Würthner F, Awale S, Bringmann G. Tshitenge DT, et al. Among authors: brun r. J Nat Prod. 2019 Nov 22;82(11):3150-3164. doi: 10.1021/acs.jnatprod.9b00755. Epub 2019 Oct 20. J Nat Prod. 2019. PMID: 31630523

8

An Unusually Broad Series of Seven Cyclombandakamines, Bridged Dimeric Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ealaensis.

Tshitenge DT, Bruhn T, Feineis D, Mudogo V, Kaiser M, Brun R, Bringmann G. Tshitenge DT, et al. Among authors: brun r. Sci Rep. 2019 Jul 8;9(1):9812. doi: 10.1038/s41598-019-46336-z. Sci Rep. 2019. PMID: 31285489 Free PMC article.

9

Antiprotozoal dimeric naphthylisoquinolines, mbandakamines B₃ and B₄, and related 5,8'-coupled monomeric alkaloids, ikelacongolines A-D, from a Congolese Ancistrocladus liana.

Mufusama JP, Feineis D, Mudogo V, Kaiser M, Brun R, Bringmann G. Mufusama JP, et al. Among authors: brun r. RSC Adv. 2019 Apr 16;9(21):12034-12046. doi: 10.1039/c9ra01784d. eCollection 2019 Apr 12. RSC Adv. 2019. PMID: 35517005 Free PMC article.

10

Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents.

Saccoliti F, Madia VN, Tudino V, De Leo A, Pescatori L, Messore A, De Vita D, Scipione L, Brun R, Kaiser M, Mäser P, Calvet CM, Jennings GK, Podust LM, Pepe G, Cirilli R, Faggi C, Di Marco A, Battista MR, Summa V, Costi R, Di Santo R. Saccoliti F, et al. Among authors: brun r. J Med Chem. 2019 Feb 14;62(3):1330-1347. doi: 10.1021/acs.jmedchem.8b01464. Epub 2019 Jan 23. J Med Chem. 2019. PMID: 30615444

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