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Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure.
van Oort RJ, McCauley MD, Dixit SS, Pereira L, Yang Y, Respress JL, Wang Q, De Almeida AC, Skapura DG, Anderson ME, Bers DM, Wehrens XH. van Oort RJ, et al. Among authors: respress jl. Circulation. 2010 Dec 21;122(25):2669-79. doi: 10.1161/CIRCULATIONAHA.110.982298. Epub 2010 Nov 15. Circulation. 2010. PMID: 21098440 Free PMC article.
Role of RyR2 phosphorylation at S2814 during heart failure progression.
Respress JL, van Oort RJ, Li N, Rolim N, Dixit SS, deAlmeida A, Voigt N, Lawrence WS, Skapura DG, Skårdal K, Wisløff U, Wieland T, Ai X, Pogwizd SM, Dobrev D, Wehrens XH. Respress JL, et al. Circ Res. 2012 May 25;110(11):1474-83. doi: 10.1161/CIRCRESAHA.112.268094. Epub 2012 Apr 17. Circ Res. 2012. PMID: 22511749 Free PMC article.
Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model.
Li N, Chiang DY, Wang S, Wang Q, Sun L, Voigt N, Respress JL, Ather S, Skapura DG, Jordan VK, Horrigan FT, Schmitz W, Müller FU, Valderrabano M, Nattel S, Dobrev D, Wehrens XHT. Li N, et al. Among authors: respress jl. Circulation. 2014 Mar 25;129(12):1276-1285. doi: 10.1161/CIRCULATIONAHA.113.006611. Epub 2014 Jan 7. Circulation. 2014. PMID: 24398018 Free PMC article.
CaMKII-dependent phosphorylation of cardiac ryanodine receptors regulates cell death in cardiac ischemia/reperfusion injury.
Di Carlo MN, Said M, Ling H, Valverde CA, De Giusti VC, Sommese L, Palomeque J, Aiello EA, Skapura DG, Rinaldi G, Respress JL, Brown JH, Wehrens XH, Salas MA, Mattiazzi A. Di Carlo MN, et al. Among authors: respress jl. J Mol Cell Cardiol. 2014 Sep;74:274-83. doi: 10.1016/j.yjmcc.2014.06.004. Epub 2014 Jun 17. J Mol Cell Cardiol. 2014. PMID: 24949568 Free PMC article.
CaMKIIδ mediates β-adrenergic effects on RyR2 phosphorylation and SR Ca(2+) leak and the pathophysiological response to chronic β-adrenergic stimulation.
Grimm M, Ling H, Willeford A, Pereira L, Gray CB, Erickson JR, Sarma S, Respress JL, Wehrens XH, Bers DM, Brown JH. Grimm M, et al. Among authors: respress jl. J Mol Cell Cardiol. 2015 Aug;85:282-91. doi: 10.1016/j.yjmcc.2015.06.007. Epub 2015 Jun 14. J Mol Cell Cardiol. 2015. PMID: 26080362 Free PMC article.
Transthoracic echocardiography in mice.
Respress JL, Wehrens XH. Respress JL, et al. J Vis Exp. 2010 May 28;(39):1738. doi: 10.3791/1738. J Vis Exp. 2010. PMID: 20517201 Free PMC article.
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