Rennie PS - Search Results

1

ETS transcription factors as emerging drug targets in cancer.

Hsing M, Wang Y, Rennie PS, Cox ME, Cherkasov A. Hsing M, et al. Among authors: rennie ps. Med Res Rev. 2020 Jan;40(1):413-430. doi: 10.1002/med.21575. Epub 2019 Mar 29. Med Res Rev. 2020. PMID: 30927317 Review.

2

Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer.

Butler MS, Roshan-Moniri M, Hsing M, Lau D, Kim A, Yen P, Mroczek M, Nouri M, Lien S, Axerio-Cilies P, Dalal K, Yau C, Ghaidi F, Guo Y, Yamazaki T, Lawn S, Gleave ME, Gregory-Evans CY, McIntosh LP, Cox ME, Rennie PS, Cherkasov A. Butler MS, et al. Among authors: rennie ps. Oncotarget. 2017 Jun 27;8(26):42438-42454. doi: 10.18632/oncotarget.17124. Oncotarget. 2017. PMID: 28465491 Free PMC article.

3

Therapeutic Inhibition of Myc in Cancer. Structural Bases and Computer-Aided Drug Discovery Approaches.

Carabet LA, Rennie PS, Cherkasov A. Carabet LA, et al. Among authors: rennie ps. Int J Mol Sci. 2018 Dec 29;20(1):120. doi: 10.3390/ijms20010120. Int J Mol Sci. 2018. PMID: 30597997 Free PMC article. Review.

4

Androgen receptor plasticity and its implications for prostate cancer therapy.

Snow O, Lallous N, Singh K, Lack N, Rennie P, Cherkasov A. Snow O, et al. Cancer Treat Rev. 2019 Dec;81:101871. doi: 10.1016/j.ctrv.2019.05.001. Epub 2019 Jun 11. Cancer Treat Rev. 2019. PMID: 31698174 Review.

5

Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening.

Axerio-Cilies P, Lack NA, Nayana MR, Chan KH, Yeung A, Leblanc E, Guns ES, Rennie PS, Cherkasov A. Axerio-Cilies P, et al. Among authors: rennie ps. J Med Chem. 2011 Sep 22;54(18):6197-205. doi: 10.1021/jm200532b. Epub 2011 Aug 29. J Med Chem. 2011. PMID: 21846139

6

Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening.

Lack NA, Axerio-Cilies P, Tavassoli P, Han FQ, Chan KH, Feau C, LeBlanc E, Guns ET, Guy RK, Rennie PS, Cherkasov A. Lack NA, et al. Among authors: rennie ps. J Med Chem. 2011 Dec 22;54(24):8563-73. doi: 10.1021/jm201098n. Epub 2011 Nov 18. J Med Chem. 2011. PMID: 22047606 Free PMC article.

7

Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer.

Lallous N, Dalal K, Cherkasov A, Rennie PS. Lallous N, et al. Among authors: rennie ps. Int J Mol Sci. 2013 Jun 14;14(6):12496-519. doi: 10.3390/ijms140612496. Int J Mol Sci. 2013. PMID: 23771019 Free PMC article. Review.

8

Discovery of 1H-indole-2-carboxamides as novel inhibitors of the androgen receptor binding function 3 (BF3).

Ban F, Leblanc E, Li H, Munuganti RS, Frewin K, Rennie PS, Cherkasov A. Ban F, et al. Among authors: rennie ps. J Med Chem. 2014 Aug 14;57(15):6867-72. doi: 10.1021/jm500684r. Epub 2014 Jul 25. J Med Chem. 2014. PMID: 25025737

9

Discovery of small-molecule inhibitors selectively targeting the DNA-binding domain of the human androgen receptor.

Li H, Ban F, Dalal K, Leblanc E, Frewin K, Ma D, Adomat H, Rennie PS, Cherkasov A. Li H, et al. Among authors: rennie ps. J Med Chem. 2014 Aug 14;57(15):6458-67. doi: 10.1021/jm500802j. Epub 2014 Aug 4. J Med Chem. 2014. PMID: 25062331

10

Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.

Dalal K, Roshan-Moniri M, Sharma A, Li H, Ban F, Hessein M, Hsing M, Singh K, LeBlanc E, Dehm S, Tomlinson Guns ES, Cherkasov A, Rennie PS. Dalal K, et al. Among authors: rennie ps. J Biol Chem. 2014 Sep 19;289(38):26417-26429. doi: 10.1074/jbc.M114.553818. Epub 2014 Aug 1. J Biol Chem. 2014. PMID: 25086042 Free PMC article.

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