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Transcription factor dimerization activates the p300 acetyltransferase.
Ortega E, Rengachari S, Ibrahim Z, Hoghoughi N, Gaucher J, Holehouse AS, Khochbin S, Panne D. Ortega E, et al. Among authors: rengachari s. Nature. 2018 Oct;562(7728):538-544. doi: 10.1038/s41586-018-0621-1. Epub 2018 Oct 15. Nature. 2018. PMID: 30323286 Free PMC article.
Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor.
Lefranc J, Schulze VK, Hillig RC, Briem H, Prinz F, Mengel A, Heinrich T, Balint J, Rengachari S, Irlbacher H, Stöckigt D, Bömer U, Bader B, Gradl SN, Nising CF, von Nussbaum F, Mumberg D, Panne D, Wengner AM. Lefranc J, et al. Among authors: rengachari s. J Med Chem. 2020 Jan 23;63(2):601-612. doi: 10.1021/acs.jmedchem.9b01460. Epub 2020 Jan 10. J Med Chem. 2020. PMID: 31859507
The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes.
Rengachari S, Bezerra GA, Riegler-Berket L, Gruber CC, Sturm C, Taschler U, Boeszoermenyi A, Dreveny I, Zimmermann R, Gruber K, Oberer M. Rengachari S, et al. Biochim Biophys Acta. 2012 Jul;1821(7):1012-21. doi: 10.1016/j.bbalip.2012.04.006. Epub 2012 Apr 27. Biochim Biophys Acta. 2012. PMID: 22561231 Free PMC article.
Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
Aschauer P, Rengachari S, Lichtenegger J, Schittmayer M, Das KM, Mayer N, Breinbauer R, Birner-Gruenberger R, Gruber CC, Zimmermann R, Gruber K, Oberer M. Aschauer P, et al. Among authors: rengachari s. Biochim Biophys Acta. 2016 May;1861(5):462-70. doi: 10.1016/j.bbalip.2016.02.005. Epub 2016 Feb 9. Biochim Biophys Acta. 2016. PMID: 26869448 Free article.
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