Ren Y - Search Results

1

PTPN11 Plays Oncogenic Roles and Is a Therapeutic Target for BRAF Wild-Type Melanomas.

Hill KS, Roberts ER, Wang X, Marin E, Park TD, Son S, Ren Y, Fang B, Yoder S, Kim S, Wan L, Sarnaik AA, Koomen JM, Messina JL, Teer JK, Kim Y, Wu J, Chalfant CE, Kim M. Hill KS, et al. Among authors: ren y. Mol Cancer Res. 2019 Feb;17(2):583-593. doi: 10.1158/1541-7786.MCR-18-0777. Epub 2018 Oct 24. Mol Cancer Res. 2019. PMID: 30355677 Free PMC article.

2

Simultaneous suppression of Erk and Akt/PKB activation by a Gab1 pleckstrin homology (PH) domain decoy.

Ren Y, Wu J. Ren Y, et al. Anticancer Res. 2003 Jul-Aug;23(4):3231-6. Anticancer Res. 2003. PMID: 12926057

3

Critical role of Shp2 in tumor growth involving regulation of c-Myc.

Ren Y, Chen Z, Chen L, Fang B, Win-Piazza H, Haura E, Koomen JM, Wu J. Ren Y, et al. Genes Cancer. 2010 Oct;1(10):994-1007. doi: 10.1177/1947601910395582. Genes Cancer. 2010. PMID: 21442024 Free PMC article.

4

Inhibition of Shp2 suppresses mutant EGFR-induced lung tumors in transgenic mouse model of lung adenocarcinoma.

Schneeberger VE, Ren Y, Luetteke N, Huang Q, Chen L, Lawrence HR, Lawrence NJ, Haura EB, Koomen JM, Coppola D, Wu J. Schneeberger VE, et al. Among authors: ren y. Oncotarget. 2015 Mar 20;6(8):6191-202. doi: 10.18632/oncotarget.3356. Oncotarget. 2015. PMID: 25730908 Free PMC article.

5

JAK1 truncating mutations in gynecologic cancer define new role of cancer-associated protein tyrosine kinase aberrations.

Ren Y, Zhang Y, Liu RZ, Fenstermacher DA, Wright KL, Teer JK, Wu J. Ren Y, et al. Sci Rep. 2013 Oct 24;3:3042. doi: 10.1038/srep03042. Sci Rep. 2013. PMID: 24154688 Free PMC article.

6

Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor.

Ren Y, Meng S, Mei L, Zhao ZJ, Jove R, Wu J. Ren Y, et al. J Biol Chem. 2004 Feb 27;279(9):8497-505. doi: 10.1074/jbc.M312575200. Epub 2003 Dec 8. J Biol Chem. 2004. PMID: 14665621 Free article.

7

Shp2E76K mutant confers cytokine-independent survival of TF-1 myeloid cells by up-regulating Bcl-XL.

Ren Y, Chen Z, Chen L, Woods NT, Reuther GW, Cheng JQ, Wang HG, Wu J. Ren Y, et al. J Biol Chem. 2007 Dec 14;282(50):36463-73. doi: 10.1074/jbc.M705789200. Epub 2007 Oct 17. J Biol Chem. 2007. PMID: 17942397 Free PMC article.

8

PLK1 stabilizes a MYC-dependent kinase network in aggressive B cell lymphomas.

Ren Y, Bi C, Zhao X, Lwin T, Wang C, Yuan J, Silva AS, Shah BD, Fang B, Li T, Koomen JM, Jiang H, Chavez JC, Pham LV, Sudalagunta PR, Wan L, Wang X, Dalton WS, Moscinski LC, Shain KH, Vose J, Cleveland JL, Sotomayor EM, Fu K, Tao J. Ren Y, et al. J Clin Invest. 2018 Dec 3;128(12):5517-5530. doi: 10.1172/JCI122533. Epub 2018 Nov 5. J Clin Invest. 2018. PMID: 30260324 Free PMC article.

9

Regulation of the mitogen-activated protein kinase signaling pathway by SHP2.

Cunnick JM, Meng S, Ren Y, Desponts C, Wang HG, Djeu JY, Wu J. Cunnick JM, et al. Among authors: ren y. J Biol Chem. 2002 Mar 15;277(11):9498-504. doi: 10.1074/jbc.M110547200. Epub 2002 Jan 4. J Biol Chem. 2002. PMID: 11779868 Free article.

10

Discovery of a novel shp2 protein tyrosine phosphatase inhibitor.

Chen L, Sung SS, Yip ML, Lawrence HR, Ren Y, Guida WC, Sebti SM, Lawrence NJ, Wu J. Chen L, et al. Among authors: ren y. Mol Pharmacol. 2006 Aug;70(2):562-70. doi: 10.1124/mol.106.025536. Epub 2006 May 22. Mol Pharmacol. 2006. PMID: 16717135

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