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Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency.
Scekic-Zahirovic J, Benetton C, Brunet A, Ye X, Logunov E, Douchamps V, Megat S, Andry V, Kan VWY, Stuart-Lopez G, Gilet J, Guillot SJ, Dirrig-Grosch S, Gorin C, Trombini M, Dieterle S, Sinniger J, Fischer M, René F, Gunes Z, Kessler P, Dupuis L, Pradat PF, Goumon Y, Goutagny R, Marchand-Pauvert V, Liebscher S, Rouaux C. Scekic-Zahirovic J, et al. Among authors: rene f. Sci Transl Med. 2024 Mar 13;16(738):eadg3665. doi: 10.1126/scitranslmed.adg3665. Epub 2024 Mar 13. Sci Transl Med. 2024. PMID: 38478631
Nogo provides a molecular marker for diagnosis of amyotrophic lateral sclerosis.
Dupuis L, Gonzalez de Aguilar JL, di Scala F, Rene F, de Tapia M, Pradat PF, Lacomblez L, Seihlan D, Prinjha R, Walsh FS, Meininger V, Loeffler JP. Dupuis L, et al. Among authors: rene f. Neurobiol Dis. 2002 Aug;10(3):358-65. doi: 10.1006/nbdi.2002.0522. Neurobiol Dis. 2002. PMID: 12270696
Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.
Scekic-Zahirovic J, Oussini HE, Mersmann S, Drenner K, Wagner M, Sun Y, Allmeroth K, Dieterlé S, Sinniger J, Dirrig-Grosch S, René F, Dormann D, Haass C, Ludolph AC, Lagier-Tourenne C, Storkebaum E, Dupuis L. Scekic-Zahirovic J, et al. Among authors: rene f. Acta Neuropathol. 2017 Jun;133(6):887-906. doi: 10.1007/s00401-017-1687-9. Epub 2017 Feb 28. Acta Neuropathol. 2017. PMID: 28243725 Free PMC article.
Amyotrophic lateral sclerosis: all roads lead to Rome.
Gonzalez de Aguilar JL, Echaniz-Laguna A, Fergani A, René F, Meininger V, Loeffler JP, Dupuis L. Gonzalez de Aguilar JL, et al. Among authors: rene f. J Neurochem. 2007 Jun;101(5):1153-60. doi: 10.1111/j.1471-4159.2006.04408.x. Epub 2007 Jan 23. J Neurochem. 2007. PMID: 17250677 Free article. Review.
Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse model.
Rouaux C, Panteleeva I, René F, Gonzalez de Aguilar JL, Echaniz-Laguna A, Dupuis L, Menger Y, Boutillier AL, Loeffler JP. Rouaux C, et al. Among authors: rene f. J Neurosci. 2007 May 23;27(21):5535-45. doi: 10.1523/JNEUROSCI.1139-07.2007. J Neurosci. 2007. PMID: 17522299 Free PMC article.
69 results