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Altered ubiquitin signaling induces Alzheimer's disease-like hallmarks in a three-dimensional human neural cell culture model.
Maniv I, Sarji M, Bdarneh A, Feldman A, Ankawa R, Koren E, Magid-Gold I, Reis N, Soteriou D, Salomon-Zimri S, Lavy T, Kesselman E, Koifman N, Kurz T, Kleifeld O, Michaelson D, van Leeuwen FW, Verheijen BM, Fuchs Y, Glickman MH. Maniv I, et al. Among authors: reis n. Nat Commun. 2023 Sep 22;14(1):5922. doi: 10.1038/s41467-023-41545-7. Nat Commun. 2023. PMID: 37739965 Free PMC article.
Structure of ubiquitylated-Rpn10 provides insight into its autoregulation mechanism.
Keren-Kaplan T, Zeev Peters L, Levin-Kravets O, Attali I, Kleifeld O, Shohat N, Artzi S, Zucker O, Pilzer I, Reis N, Glickman MH, Ben-Aroya S, Prag G. Keren-Kaplan T, et al. Among authors: reis n. Nat Commun. 2016 Oct 4;7:12960. doi: 10.1038/ncomms12960. Nat Commun. 2016. PMID: 27698474 Free PMC article.
Extended ubiquitin species are protein-based DUB inhibitors.
Krutauz D, Reis N, Nakasone MA, Siman P, Zhang D, Kirkpatrick DS, Gygi SP, Brik A, Fushman D, Glickman MH. Krutauz D, et al. Among authors: reis n. Nat Chem Biol. 2014 Aug;10(8):664-70. doi: 10.1038/nchembio.1574. Epub 2014 Jul 6. Nat Chem Biol. 2014. PMID: 24997605 Free PMC article.
Inhibition of proteasome reveals basal mitochondrial ubiquitination.
Sulkshane P, Duek I, Ram J, Thakur A, Reis N, Ziv T, Glickman MH. Sulkshane P, et al. Among authors: reis n. J Proteomics. 2020 Oct 30;229:103949. doi: 10.1016/j.jprot.2020.103949. Epub 2020 Aug 31. J Proteomics. 2020. PMID: 32882436 Free article.
342 results