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Synthesis and biological evaluation of a new series of hexahydro-2H-pyrano[3,2-c]quinolines as novel selective σ1 receptor ligands.
Díaz JL, Christmann U, Fernández A, Luengo M, Bordas M, Enrech R, Carro M, Pascual R, Burgueño J, Merlos M, Benet-Buchholz J, Cerón-Bertran J, Ramírez J, Reinoso RF, Fernández de Henestrosa AR, Vela JM, Almansa C. Díaz JL, et al. Among authors: reinoso rf. J Med Chem. 2013 May 9;56(9):3656-65. doi: 10.1021/jm400181k. Epub 2013 Apr 26. J Med Chem. 2013. PMID: 23560650
Bicyclic Diazepinones as Dual Ligands of the α2δ-1 Subunit of Voltage-Gated Calcium Channels and the Norepinephrine Transporter.
Díaz JL, Cuevas F, Pazos G, Álvarez-Bercedo P, Oliva AI, Sarmentero MÁ, Font D, Jiménez-Aquino A, Morón M, Port A, Pascual R, Dordal A, Portillo-Salido E, Reinoso RF, Vela JM, Almansa C. Díaz JL, et al. Among authors: reinoso rf. J Med Chem. 2021 Feb 25;64(4):2167-2185. doi: 10.1021/acs.jmedchem.0c01867. Epub 2021 Feb 16. J Med Chem. 2021. PMID: 33591743
Discovery and characterization of 4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (LAS38096), a potent, selective, and efficacious A2B adenosine receptor antagonist.
Vidal B, Nueda A, Esteve C, Domenech T, Benito S, Reinoso RF, Pont M, Calbet M, López R, Cadavid MI, Loza MI, Cárdenas A, Godessart N, Beleta J, Warrellow G, Ryder H. Vidal B, et al. Among authors: reinoso rf. J Med Chem. 2007 May 31;50(11):2732-6. doi: 10.1021/jm061333v. Epub 2007 May 1. J Med Chem. 2007. PMID: 17469811
Piperazinyl Bicyclic Derivatives as Selective Ligands of the α2δ-1 Subunit of Voltage-Gated Calcium Channels.
Fernández A, Díaz JL, García M, Rodríguez-Escrich S, Lorente A, Enrech R, Dordal A, Portillo-Salido E, Porras M, Fernández B, Reinoso RF, Vela JM, Almansa C. Fernández A, et al. Among authors: reinoso rf. ACS Med Chem Lett. 2021 Oct 5;12(11):1802-1809. doi: 10.1021/acsmedchemlett.1c00416. eCollection 2021 Nov 11. ACS Med Chem Lett. 2021. PMID: 34795870 Free PMC article.
Biaryl analogues of teriflunomide as potent DHODH inhibitors.
Erra M, Moreno I, Sanahuja J, Andrés M, Reinoso RF, Lozoya E, Pizcueta P, Godessart N, Castro-Palomino JC. Erra M, et al. Among authors: reinoso rf. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7268-72. doi: 10.1016/j.bmcl.2011.10.052. Epub 2011 Oct 20. Bioorg Med Chem Lett. 2011. PMID: 22078215
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