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Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia.
Morrow MR, Batchuluun B, Wu J, Ahmadi E, Leroux JM, Mohammadi-Shemirani P, Desjardins EM, Wang Z, Tsakiridis EE, Lavoie DCT, Reihani A, Smith BK, Kwiecien JM, Lally JSV, Nero TL, Parker MW, Ask K, Scott JW, Jiang L, Paré G, Pinkosky SL, Steinberg GR. Morrow MR, et al. Among authors: reihani a. Cell Metab. 2022 Jun 7;34(6):919-936.e8. doi: 10.1016/j.cmet.2022.05.004. Cell Metab. 2022. PMID: 35675800 Free article.
Myeloid-specific deletion of activating transcription factor 6 alpha increases CD11b+ macrophage subpopulations and aggravates lung fibrosis.
Mekhael O, Revill SD, Hayat AI, Cass SP, MacDonald K, Vierhout M, Ayoub A, Reihani A, Padwal M, Imani J, Ayaub E, Yousof T, Dvorkin-Gheva A, Rullo A, Hirota JA, Richards CD, Bridgewater D, Stämpfli MR, Hambly N, Naqvi A, Kolb MR, Ask K. Mekhael O, et al. Among authors: reihani a. Immunol Cell Biol. 2023 May;101(5):412-427. doi: 10.1111/imcb.12637. Epub 2023 Apr 4. Immunol Cell Biol. 2023. PMID: 36862017
Increased Monocyte-Derived CD11b+ Macrophage Subpopulations Following Cigarette Smoke Exposure Are Associated With Impaired Bleomycin-Induced Tissue Remodelling.
Cass SP, Mekhael O, Thayaparan D, McGrath JJC, Revill SD, Fantauzzi MF, Wang P, Reihani A, Hayat AI, Stevenson CS, Dvorkin-Gheva A, Botelho FM, Stämpfli MR, Ask K. Cass SP, et al. Among authors: reihani a. Front Immunol. 2021 Sep 16;12:740330. doi: 10.3389/fimmu.2021.740330. eCollection 2021. Front Immunol. 2021. PMID: 34603325 Free PMC article.
Cigarette smoke augments CSF3 expression in neutrophils to compromise alveolar-capillary barrier function during influenza infection.
McGrath JJC, Vanderstocken G, Dvorkin-Gheva A, Cass SP, Afkhami S, Fantauzzi MF, Thayaparan D, Reihani A, Wang P, Beaulieu A, Shen P, Morissette M, Jiménez-Saiz R, Revill SD, Tabuchi A, Zabini D, Lee WL, Richards CD, Miller MS, Ask K, Kuebler WM, Simpson JA, Stämpfli MR. McGrath JJC, et al. Among authors: reihani a. Eur Respir J. 2022 Aug 25;60(2):2102049. doi: 10.1183/13993003.02049-2021. Print 2022 Aug. Eur Respir J. 2022. PMID: 35058252 Free article.
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