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107 results

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Page 1
Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy.
Ye H, Chen C, Wu H, Zheng K, Martín-Adrados B, Caparros E, Francés R, Nelson LJ, Gómez Del Moral M, Asensio I, Vaquero J, Bañares R, Ávila MA, Andrade RJ, Isabel Lucena M, Martínez-Chantar ML, Reeves HL, Masson S, Blumberg RS, Gracia-Sancho J, Nevzorova YA, Martínez-Naves E, Cubero FJ. Ye H, et al. Among authors: reeves hl. Cell Death Dis. 2022 Feb 10;13(2):143. doi: 10.1038/s41419-022-04580-8. Cell Death Dis. 2022. PMID: 35145060 Free PMC article.
The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury.
Barbier-Torres L, Iruzubieta P, Fernández-Ramos D, Delgado TC, Taibo D, Guitiérrez-de-Juan V, Varela-Rey M, Azkargorta M, Navasa N, Fernández-Tussy P, Zubiete-Franco I, Simon J, Lopitz-Otsoa F, Lachiondo-Ortega S, Crespo J, Masson S, McCain MV, Villa E, Reeves H, Elortza F, Lucena MI, Hernández-Alvarez MI, Zorzano A, Andrade RJ, Lu SC, Mato JM, Anguita J, Rincón M, Martínez-Chantar ML. Barbier-Torres L, et al. Nat Commun. 2017 Dec 12;8(1):2068. doi: 10.1038/s41467-017-01970-x. Nat Commun. 2017. PMID: 29233977 Free PMC article.
Anti-miR-518d-5p overcomes liver tumor cell death resistance through mitochondrial activity.
Fernández-Tussy P, Rodríguez-Agudo R, Fernández-Ramos D, Barbier-Torres L, Zubiete-Franco I, Davalillo SL, Herraez E, Goikoetxea-Usandizaga N, Lachiondo-Ortega S, Simón J, Lopitz-Otsoa F, Juan VG, McCain MV, Perugorria MJ, Mabe J, Navasa N, Rodrigues CMP, Fabregat I, Boix L, Sapena V, Anguita J, Lu SC, Mato JM, Banales JM, Villa E, Reeves HL, Bruix J, Reig M, Marin JJG, Delgado TC, Martínez-Chantar ML. Fernández-Tussy P, et al. Among authors: reeves hl. Cell Death Dis. 2021 May 28;12(6):555. doi: 10.1038/s41419-021-03827-0. Cell Death Dis. 2021. PMID: 34050139 Free PMC article.
Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage.
González-Recio I, Simón J, Goikoetxea-Usandizaga N, Serrano-Maciá M, Mercado-Gómez M, Rodríguez-Agudo R, Lachiondo-Ortega S, Gil-Pitarch C, Fernández-Rodríguez C, Castellana D, Latasa MU, Abecia L, Anguita J, Delgado TC, Iruzubieta P, Crespo J, Hardy S, Petrov PD, Jover R, Avila MA, Martín C, Schaeper U, Tremblay ML, Dear JW, Masson S, McCain MV, Reeves HL, Andrade RJ, Lucena MI, Buccella D, Martínez-Cruz LA, Martínez-Chantar ML. González-Recio I, et al. Among authors: reeves hl. Nat Commun. 2022 Nov 25;13(1):6816. doi: 10.1038/s41467-022-34262-0. Nat Commun. 2022. PMID: 36433951 Free PMC article.
COVID-19 and liver cancer: lost patients and larger tumours.
Geh D, Watson R, Sen G, French JJ, Hammond J, Turner P, Hoare T, Anderson K, McNeil M, McPherson S, Masson S, Dyson J, Donnelly M, MacDougal L, Patel P, Hudson M, Anstee QM, White S, Robinson S, Pandanaboyana S, Walker L, McCain M, Bury Y, Raman S, Burt A, Parkinson D, Haugk B, Darne A, Wadd N, Asghar S, Mariappan L, Margetts J, Stenberg B, Scott J, Littler P, Manas DM, Reeves HL. Geh D, et al. Among authors: reeves hl. BMJ Open Gastroenterol. 2022 Apr;9(1):e000794. doi: 10.1136/bmjgast-2021-000794. BMJ Open Gastroenterol. 2022. PMID: 35450934 Free PMC article. Review.
Neutrophils as potential therapeutic targets in hepatocellular carcinoma.
Geh D, Leslie J, Rumney R, Reeves HL, Bird TG, Mann DA. Geh D, et al. Among authors: reeves hl. Nat Rev Gastroenterol Hepatol. 2022 Apr;19(4):257-273. doi: 10.1038/s41575-021-00568-5. Epub 2022 Jan 12. Nat Rev Gastroenterol Hepatol. 2022. PMID: 35022608 Review.
c-Rel-dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis.
Leslie J, Hunter JE, Collins A, Rushton A, Russell LG, Ramon-Gil E, Laszczewska M, McCain M, Zaki MYW, Knox A, Seow Y, Sabater L, Geh D, Perkins ND, Reeves HL, Tiniakos D, Mann DA, Oakley F. Leslie J, et al. Among authors: reeves hl. Hepatology. 2023 Oct 1;78(4):1050-1063. doi: 10.1002/hep.32781. Epub 2023 Sep 27. Hepatology. 2023. PMID: 36089330 Free PMC article.
107 results