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Functional brain imaging in larval zebrafish for characterising the effects of seizurogenic compounds acting via a range of pharmacological mechanisms.
Winter MJ, Pinion J, Tochwin A, Takesono A, Ball JS, Grabowski P, Metz J, Trznadel M, Tse K, Redfern WS, Hetheridge MJ, Goodfellow M, Randall AD, Tyler CR. Winter MJ, et al. Among authors: redfern ws. Br J Pharmacol. 2021 Jul;178(13):2671-2689. doi: 10.1111/bph.15458. Epub 2021 May 5. Br J Pharmacol. 2021. PMID: 33768524 Free article.
Approaches to seizure risk assessment in preclinical drug discovery.
Easter A, Bell ME, Damewood JR Jr, Redfern WS, Valentin JP, Winter MJ, Fonck C, Bialecki RA. Easter A, et al. Among authors: redfern ws. Drug Discov Today. 2009 Sep;14(17-18):876-84. doi: 10.1016/j.drudis.2009.06.003. Epub 2009 Jun 21. Drug Discov Today. 2009. PMID: 19545644 Review.
Validation of the use of zebrafish larvae in visual safety assessment.
Richards FM, Alderton WK, Kimber GM, Liu Z, Strang I, Redfern WS, Valentin JP, Winter MJ, Hutchinson TH. Richards FM, et al. Among authors: redfern ws. J Pharmacol Toxicol Methods. 2008 Jul-Aug;58(1):50-8. doi: 10.1016/j.vascn.2008.04.002. Epub 2008 May 2. J Pharmacol Toxicol Methods. 2008. PMID: 18541443
Pharmacological validation of individual animal locomotion, temperature and behavioural analysis in group-housed rats using a novel automated home cage analysis system: A comparison with the modified Irwin test.
Tse K, Sillito R, Keerie A, Collier R, Grant C, Karp NA, Vickers C, Chapman K, Armstrong JD, Redfern WS. Tse K, et al. Among authors: redfern ws. J Pharmacol Toxicol Methods. 2018 Nov-Dec;94(Pt 1):1-13. doi: 10.1016/j.vascn.2018.03.008. Epub 2018 Apr 1. J Pharmacol Toxicol Methods. 2018. PMID: 29614333
46 results