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Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease.
Lindner S, Miltiadous O, Ramos RJF, Paredes J, Kousa AI, Dai A, Fei T, Lauder E, Frame J, Waters NR, Sadeghi K, Armijo GK, Ghale R, Victor K, Gipson B, Monette S, Russo MV, Nguyen CL, Slingerland J, Taur Y, Markey KA, Andrlova H, Giralt S, Perales MA, Reddy P, Peled JU, Smith M, Cross JR, Burgos da Silva M, Campbell C, van den Brink MRM. Lindner S, et al. Among authors: reddy p. Nat Microbiol. 2024 Mar;9(3):614-630. doi: 10.1038/s41564-024-01617-w. Epub 2024 Mar 1. Nat Microbiol. 2024. PMID: 38429422
Graft-versus-host disease.
Choi S, Reddy P. Choi S, et al. Among authors: reddy p. Panminerva Med. 2010 Jun;52(2):111-24. Panminerva Med. 2010. PMID: 20517195 Review.
Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease.
Mathewson ND, Jenq R, Mathew AV, Koenigsknecht M, Hanash A, Toubai T, Oravecz-Wilson K, Wu SR, Sun Y, Rossi C, Fujiwara H, Byun J, Shono Y, Lindemans C, Calafiore M, Schmidt TM, Honda K, Young VB, Pennathur S, van den Brink M, Reddy P. Mathewson ND, et al. Among authors: reddy p. Nat Immunol. 2016 May;17(5):505-513. doi: 10.1038/ni.3400. Epub 2016 Mar 21. Nat Immunol. 2016. PMID: 26998764 Free PMC article.
Microbial metabolites and graft versus host disease.
Riwes M, Reddy P. Riwes M, et al. Among authors: reddy p. Am J Transplant. 2018 Jan;18(1):23-29. doi: 10.1111/ajt.14443. Epub 2017 Aug 29. Am J Transplant. 2018. PMID: 28742948 Free article. Review.
The Microbiome and Hematopoietic Cell Transplantation: Past, Present, and Future.
Andermann TM, Peled JU, Ho C, Reddy P, Riches M, Storb R, Teshima T, van den Brink MRM, Alousi A, Balderman S, Chiusolo P, Clark WB, Holler E, Howard A, Kean LS, Koh AY, McCarthy PL, McCarty JM, Mohty M, Nakamura R, Rezvani K, Segal BH, Shaw BE, Shpall EJ, Sung AD, Weber D, Whangbo J, Wingard JR, Wood WA, Perales MA, Jenq RR, Bhatt AS; Blood and Marrow Transplant Clinical Trials Network. Andermann TM, et al. Among authors: reddy p. Biol Blood Marrow Transplant. 2018 Jul;24(7):1322-1340. doi: 10.1016/j.bbmt.2018.02.009. Epub 2018 Feb 19. Biol Blood Marrow Transplant. 2018. PMID: 29471034 Free PMC article. Review. No abstract available.
Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease.
Zhao D, Kim YH, Jeong S, Greenson JK, Chaudhry MS, Hoepting M, Anderson ER, van den Brink MR, Peled JU, Gomes AL, Slingerland AE, Donovan MJ, Harris AC, Levine JE, Ozbek U, Hooper LV, Stappenbeck TS, Ver Heul A, Liu TC, Reddy P, Ferrara JL. Zhao D, et al. Among authors: reddy p. J Clin Invest. 2018 Nov 1;128(11):4970-4979. doi: 10.1172/JCI99261. Epub 2018 Sep 24. J Clin Invest. 2018. PMID: 30106382 Free PMC article. Clinical Trial.
Microbial metabolite sensor GPR43 controls severity of experimental GVHD.
Fujiwara H, Docampo MD, Riwes M, Peltier D, Toubai T, Henig I, Wu SJ, Kim S, Taylor A, Brabbs S, Liu C, Zajac C, Oravecz-Wilson K, Sun Y, Núñez G, Levine JE, van den Brink MRM, Ferrara JLM, Reddy P. Fujiwara H, et al. Among authors: reddy p. Nat Commun. 2018 Sep 10;9(1):3674. doi: 10.1038/s41467-018-06048-w. Nat Commun. 2018. PMID: 30201970 Free PMC article.
Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition.
Toubai T, Fujiwara H, Rossi C, Riwes M, Tamaki H, Zajac C, Liu C, Mathew AV, Byun J, Oravecz-Wilson K, Matsuda I, Sun Y, Peltier D, Wu J, Chen J, Seregin S, Henig I, Kim S, Brabbs S, Pennathur S, Chen G, Reddy P. Toubai T, et al. Among authors: reddy p. Nat Microbiol. 2019 May;4(5):800-812. doi: 10.1038/s41564-019-0373-1. Epub 2019 Mar 11. Nat Microbiol. 2019. PMID: 30858572 Free PMC article.
3,593 results