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The SYGMA programme of phase 3 trials to evaluate the efficacy and safety of budesonide/formoterol given 'as needed' in mild asthma: study protocols for two randomised controlled trials.
O'Byrne PM, FitzGerald JM, Zhong N, Bateman E, Barnes PJ, Keen C, Almqvist G, Pemberton K, Jorup C, Ivanov S, Reddel HK. O'Byrne PM, et al. Among authors: reddel hk. Trials. 2017 Jan 10;18(1):12. doi: 10.1186/s13063-016-1731-4. Trials. 2017. PMID: 28069068 Free PMC article.
Asthma.
Papi A, Brightling C, Pedersen SE, Reddel HK. Papi A, et al. Among authors: reddel hk. Lancet. 2018 Feb 24;391(10122):783-800. doi: 10.1016/S0140-6736(17)33311-1. Epub 2017 Dec 19. Lancet. 2018. PMID: 29273246 Review.
As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.
Bateman ED, Reddel HK, O'Byrne PM, Barnes PJ, Zhong N, Keen C, Jorup C, Lamarca R, Siwek-Posluszna A, FitzGerald JM. Bateman ED, et al. Among authors: reddel hk. N Engl J Med. 2018 May 17;378(20):1877-1887. doi: 10.1056/NEJMoa1715275. N Engl J Med. 2018. PMID: 29768147 Free article. Clinical Trial.
Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.
O'Byrne PM, FitzGerald JM, Bateman ED, Barnes PJ, Zhong N, Keen C, Jorup C, Lamarca R, Ivanov S, Reddel HK. O'Byrne PM, et al. Among authors: reddel hk. N Engl J Med. 2018 May 17;378(20):1865-1876. doi: 10.1056/NEJMoa1715274. N Engl J Med. 2018. PMID: 29768149 Free article. Clinical Trial.
As-Needed Budesonide-Formoterol in Mild Asthma.
Bateman ED, Reddel HK, FitzGerald JM. Bateman ED, et al. Among authors: reddel hk. N Engl J Med. 2018 Aug 30;379(9):898. doi: 10.1056/NEJMc1808073. N Engl J Med. 2018. PMID: 30157403 No abstract available.
Controlled Trial of Budesonide-Formoterol as Needed for Mild Asthma.
Beasley R, Holliday M, Reddel HK, Braithwaite I, Ebmeier S, Hancox RJ, Harrison T, Houghton C, Oldfield K, Papi A, Pavord ID, Williams M, Weatherall M; Novel START Study Team. Beasley R, et al. Among authors: reddel hk. N Engl J Med. 2019 May 23;380(21):2020-2030. doi: 10.1056/NEJMoa1901963. Epub 2019 May 19. N Engl J Med. 2019. PMID: 31112386 Clinical Trial.
225 results