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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 3
2004 2
2005 1
2006 1
2007 2
2008 4
2009 3
2010 1
2011 1
2012 1
2013 1
2014 3
2015 2
2016 2
2017 2
2018 1
2019 3
2020 3
2021 3
2022 4
2023 1
2024 0

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37 results

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Page 1
Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.
Picon S, Boulahjar R, Hoguet V, Baron M, Duplan I, Vallez E, Hennuyer N, Dumont J, Touche V, Dorchies E, Lasalle M, Descat A, Piveteau C, Biela A, Chaput L, Villoutreix BO, Lipka E, Sevin E, Culot M, Gosselet F, Lestavel S, Roussel P, Deprez-Poulain R, Leroux F, Staels B, Deprez B, Tailleux A, Charton J. Picon S, et al. Among authors: deprez poulain r. J Med Chem. 2023 Sep 14;66(17):11732-11760. doi: 10.1021/acs.jmedchem.2c01881. Epub 2023 Aug 28. J Med Chem. 2023. PMID: 37639383
Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.
Legru A, Verdirosa F, Vo-Hoang Y, Tassone G, Vascon F, Thomas CA, Sannio F, Corsica G, Benvenuti M, Feller G, Coulon R, Marcoccia F, Devente SR, Bouajila E, Piveteau C, Leroux F, Deprez-Poulain R, Deprez B, Licznar-Fajardo P, Crowder MW, Cendron L, Pozzi C, Mangani S, Docquier JD, Hernandez JF, Gavara L. Legru A, et al. Among authors: deprez poulain r. J Med Chem. 2022 Dec 22;65(24):16392-16419. doi: 10.1021/acs.jmedchem.2c01257. Epub 2022 Nov 30. J Med Chem. 2022. PMID: 36450011 Free article.
Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis.
Camberlein V, Fléau C, Sierocki P, Li L, Gealageas R, Bosc D, Guillaume V, Warenghem S, Leroux F, Rosell M, Cheng K, Medve L, Prigent M, Decanter M, Piveteau C, Biela A, Eveque M, Dumont J, Mpakali A, Giastas P, Herledan A, Couturier C, Haupenthal J, Lesire L, Hirsch AKH, Deprez B, Stratikos E, Bouvier M, Deprez-Poulain R. Camberlein V, et al. Among authors: deprez poulain r. Angew Chem Int Ed Engl. 2022 Sep 26;61(39):e202203560. doi: 10.1002/anie.202203560. Epub 2022 Aug 19. Angew Chem Int Ed Engl. 2022. PMID: 35904863 Free PMC article.
Identification of indole-based activators of insulin degrading enzyme.
Kraupner N, Dinh CP, Wen X, Landry V, Herledan A, Leroux F, Bosc D, Charton J, Maillard C, Warenghem S, Duplan I, Piveteau C, Hennuyer N, Staels B, Deprez B, Deprez-Poulain R. Kraupner N, et al. Among authors: deprez poulain r. Eur J Med Chem. 2022 Jan 15;228:113982. doi: 10.1016/j.ejmech.2021.113982. Epub 2021 Nov 16. Eur J Med Chem. 2022. PMID: 34815130
Modulators of hERAP2 discovered by high-throughput screening.
Laura M, Ronan G, Vy LB, Valentin G, Omar CA, Virgyl C, Piveteau C, Melissa R, Charlotte F, Sandrine W, Julie C, Julie DR, Damien B, Florence L, Peter VE, Benoit D, Rebecca DP. Laura M, et al. Among authors: rebecca dp. Eur J Med Chem. 2021 Feb 5;211:113053. doi: 10.1016/j.ejmech.2020.113053. Epub 2020 Dec 11. Eur J Med Chem. 2021. PMID: 33359953
Kinetic Target-Guided Synthesis: Reaching the Age of Maturity.
Bosc D, Camberlein V, Gealageas R, Castillo-Aguilera O, Deprez B, Deprez-Poulain R. Bosc D, et al. Among authors: deprez poulain r. J Med Chem. 2020 Apr 23;63(8):3817-3833. doi: 10.1021/acs.jmedchem.9b01183. Epub 2019 Dec 24. J Med Chem. 2020. PMID: 31820982 Review.
Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening.
Leroux F, Bosc D, Beghyn T, Hermant P, Warenghem S, Landry V, Pottiez V, Guillaume V, Charton J, Herledan A, Urata S, Liang W, Sheng L, Tang WJ, Deprez B, Deprez-Poulain R. Leroux F, et al. Among authors: deprez poulain r. Eur J Med Chem. 2019 Oct 1;179:557-566. doi: 10.1016/j.ejmech.2019.06.057. Epub 2019 Jun 24. Eur J Med Chem. 2019. PMID: 31276900 Free PMC article.
37 results