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RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and Atherogenesis in Mice.
Karunakaran D, Nguyen MA, Geoffrion M, Vreeken D, Lister Z, Cheng HS, Otte N, Essebier P, Wyatt H, Kandiah JW, Jung R, Alenghat FJ, Mompeon A, Lee R, Pan C, Gordon E, Rasheed A, Lusis AJ, Liu P, Matic LP, Hedin U, Fish JE, Guo L, Kolodgie F, Virmani R, van Gils JM, Rayner KJ. Karunakaran D, et al. Among authors: rayner kj. Circulation. 2021 Jan 12;143(2):163-177. doi: 10.1161/CIRCULATIONAHA.118.038379. Epub 2020 Nov 23. Circulation. 2021. PMID: 33222501
The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques.
van Gils JM, Derby MC, Fernandes LR, Ramkhelawon B, Ray TD, Rayner KJ, Parathath S, Distel E, Feig JL, Alvarez-Leite JI, Rayner AJ, McDonald TO, O'Brien KD, Stuart LM, Fisher EA, Lacy-Hulbert A, Moore KJ. van Gils JM, et al. Among authors: rayner kj, rayner aj. Nat Immunol. 2012 Jan 8;13(2):136-43. doi: 10.1038/ni.2205. Nat Immunol. 2012. PMID: 22231519 Free PMC article.
Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling.
Raizman JE, Chen YX, Seibert T, Hibbert B, Cuerrier CM, Salari S, Zhao X, Hu T, Shi C, Ma X, Simard T, Caravaggio J, Rayner K, Bowdish D, Moore K, O'Brien ER. Raizman JE, et al. Biochim Biophys Acta. 2013 Dec;1831(12):1721-8. doi: 10.1016/j.bbalip.2013.07.015. Epub 2013 Aug 11. Biochim Biophys Acta. 2013. PMID: 23939398
98 results