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Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K+ channels for atrial fibrillation treatment.
Burg S, Shapiro S, Peretz A, Haimov E, Redko B, Yeheskel A, Simhaev L, Engel H, Raveh A, Ben-Bassat A, Murninkas M, Polak R, Haitin Y, Etzion Y, Attali B. Burg S, et al. Among authors: raveh a. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2202926119. doi: 10.1073/pnas.2202926119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969786 Free PMC article.
Integrating in vitro and in silico approaches to evaluate the "dual functionality" of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils.
Haj E, Losev Y, Guru KrishnaKumar V, Pichinuk E, Engel H, Raveh A, Gazit E, Segal D. Haj E, et al. Among authors: raveh a. Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1565-1575. doi: 10.1016/j.bbagen.2018.04.001. Epub 2018 Apr 7. Biochim Biophys Acta Gen Subj. 2018. PMID: 29634991
Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts.
Cheng KC, Cao S, Raveh A, MacArthur R, Dranchak P, Chlipala G, Okoneski MT, Guha R, Eastman RT, Yuan J, Schultz PJ, Su XZ, Tamayo-Castillo G, Matainaho T, Clardy J, Sherman DH, Inglese J. Cheng KC, et al. Among authors: raveh a. J Nat Prod. 2015 Oct 23;78(10):2411-22. doi: 10.1021/acs.jnatprod.5b00489. Epub 2015 Oct 14. J Nat Prod. 2015. PMID: 26465675 Free PMC article.
38 results