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Single cell analysis of cribriform prostate cancer reveals cell intrinsic and tumor microenvironmental pathways of aggressive disease.
Wong HY, Sheng Q, Hesterberg AB, Croessmann S, Rios BL, Giri K, Jackson J, Miranda AX, Watkins E, Schaffer KR, Donahue M, Winkler E, Penson DF, Smith JA, Herrell SD, Luckenbaugh AN, Barocas DA, Kim YJ, Graves D, Giannico GA, Rathmell JC, Park BH, Gordetsky JB, Hurley PJ. Wong HY, et al. Among authors: rathmell jc. Nat Commun. 2022 Oct 13;13(1):6036. doi: 10.1038/s41467-022-33780-1. Nat Commun. 2022. PMID: 36229464 Free PMC article.
Cell-programmed nutrient partitioning in the tumour microenvironment.
Reinfeld BI, Madden MZ, Wolf MM, Chytil A, Bader JE, Patterson AR, Sugiura A, Cohen AS, Ali A, Do BT, Muir A, Lewis CA, Hongo RA, Young KL, Brown RE, Todd VM, Huffstater T, Abraham A, O'Neil RT, Wilson MH, Xin F, Tantawy MN, Merryman WD, Johnson RW, Williams CS, Mason EF, Mason FM, Beckermann KE, Vander Heiden MG, Manning HC, Rathmell JC, Rathmell WK. Reinfeld BI, et al. Among authors: rathmell jc, rathmell wk. Nature. 2021 May;593(7858):282-288. doi: 10.1038/s41586-021-03442-1. Epub 2021 Apr 7. Nature. 2021. PMID: 33828302 Free PMC article.
Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine.
Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker LM, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE Jr, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM. Kramer KJ, et al. Among authors: rathmell jc. Nat Commun. 2022 Jun 16;13(1):3466. doi: 10.1038/s41467-022-31142-5. Nat Commun. 2022. PMID: 35710908 Free PMC article.
T cells specific for α-myosin drive immunotherapy-related myocarditis.
Axelrod ML, Meijers WC, Screever EM, Qin J, Carroll MG, Sun X, Tannous E, Zhang Y, Sugiura A, Taylor BC, Hanna A, Zhang S, Amancherla K, Tai W, Wright JJ, Wei SC, Opalenik SR, Toren AL, Rathmell JC, Ferrell PB, Phillips EJ, Mallal S, Johnson DB, Allison JP, Moslehi JJ, Balko JM. Axelrod ML, et al. Among authors: rathmell jc. Nature. 2022 Nov;611(7937):818-826. doi: 10.1038/s41586-022-05432-3. Epub 2022 Nov 16. Nature. 2022. PMID: 36385524 Free PMC article.
Dysfunctional T cell metabolism in the tumor microenvironment.
Beckermann KE, Dudzinski SO, Rathmell JC. Beckermann KE, et al. Among authors: rathmell jc. Cytokine Growth Factor Rev. 2017 Jun;35:7-14. doi: 10.1016/j.cytogfr.2017.04.003. Epub 2017 Apr 23. Cytokine Growth Factor Rev. 2017. PMID: 28456467 Free PMC article. Review.
Metabolic Barriers to T Cell Function in Tumors.
Sugiura A, Rathmell JC. Sugiura A, et al. Among authors: rathmell jc. J Immunol. 2018 Jan 15;200(2):400-407. doi: 10.4049/jimmunol.1701041. J Immunol. 2018. PMID: 29311381 Free PMC article. Review.
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, Kondo J, Coffey RJ, Johnson MO, Rathmell JC, Sharick JT, Skala MC, Smith JA, Berlin J, Washington MK, Nickels ML, Manning HC. Schulte ML, et al. Among authors: rathmell jc. Nat Med. 2018 Feb;24(2):194-202. doi: 10.1038/nm.4464. Epub 2018 Jan 15. Nat Med. 2018. PMID: 29334372 Free PMC article.
Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.
Morioka S, Perry JSA, Raymond MH, Medina CB, Zhu Y, Zhao L, Serbulea V, Onengut-Gumuscu S, Leitinger N, Kucenas S, Rathmell JC, Makowski L, Ravichandran KS. Morioka S, et al. Among authors: rathmell jc. Nature. 2018 Nov;563(7733):714-718. doi: 10.1038/s41586-018-0735-5. Epub 2018 Nov 21. Nature. 2018. PMID: 30464343 Free PMC article.
223 results