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Nitrosative modifications of the Ca2+ release complex and actin underlie arthritis-induced muscle weakness.
Yamada T, Fedotovskaya O, Cheng AJ, Cornachione AS, Minozzo FC, Aulin C, Fridén C, Turesson C, Andersson DC, Glenmark B, Lundberg IE, Rassier DE, Westerblad H, Lanner JT. Yamada T, et al. Among authors: rassier de. Ann Rheum Dis. 2015 Oct;74(10):1907-14. doi: 10.1136/annrheumdis-2013-205007. Epub 2014 May 22. Ann Rheum Dis. 2015. PMID: 24854355 Free PMC article.
Prolonged force depression after mechanically demanding contractions is largely independent of Ca2+ and reactive oxygen species.
Kamandulis S, de Souza Leite F, Hernández A, Katz A, Brazaitis M, Bruton JD, Venckunas T, Masiulis N, Mickeviciene D, Eimantas N, Subocius A, Rassier DE, Skurvydas A, Ivarsson N, Westerblad H. Kamandulis S, et al. Among authors: de souza leite f, rassier de. FASEB J. 2017 Nov;31(11):4809-4820. doi: 10.1096/fj.201700019R. Epub 2017 Jul 17. FASEB J. 2017. PMID: 28716970
In conclusion, PLFFD caused by mechanically demanding eccentric contractions does not involve any major increase in ROS or RyR1 fragmentation.-Kamandulis, S., de Souza Leite, F., Hernandez, A., Katz, A., Brazaitis, M., Bruton, J. D., Venckunas, T., Masiulis, N., Mickevicie …
In conclusion, PLFFD caused by mechanically demanding eccentric contractions does not involve any major increase in ROS or RyR1 fragmentatio …
Oxidative hotspots on actin promote skeletal muscle weakness in rheumatoid arthritis.
Steinz MM, Persson M, Aresh B, Olsson K, Cheng AJ, Ahlstrand E, Lilja M, Lundberg TR, Rullman E, Möller KÄ, Sandor K, Ajeganova S, Yamada T, Beard N, Karlsson BC, Tavi P, Kenne E, Svensson CI, Rassier DE, Karlsson R, Friedman R, Gustafsson T, Lanner JT. Steinz MM, et al. Among authors: rassier de. JCI Insight. 2019 Mar 28;5(9):e126347. doi: 10.1172/jci.insight.126347. JCI Insight. 2019. PMID: 30920392 Free PMC article.
116 results