Rapoport B - Search Results

1

Mechanisms of Autoantibody-Induced Pathology.

Ludwig RJ, Vanhoorelbeke K, Leypoldt F, Kaya Z, Bieber K, McLachlan SM, Komorowski L, Luo J, Cabral-Marques O, Hammers CM, Lindstrom JM, Lamprecht P, Fischer A, Riemekasten G, Tersteeg C, Sondermann P, Rapoport B, Wandinger KP, Probst C, El Beidaq A, Schmidt E, Verkman A, Manz RA, Nimmerjahn F. Ludwig RJ, et al. Among authors: rapoport b. Front Immunol. 2017 May 31;8:603. doi: 10.3389/fimmu.2017.00603. eCollection 2017. Front Immunol. 2017. PMID: 28620373 Free PMC article. Review.

2

Thyroid Autoantibodies Display both "Original Antigenic Sin" and Epitope Spreading.

McLachlan SM, Rapoport B. McLachlan SM, et al. Among authors: rapoport b. Front Immunol. 2017 Dec 20;8:1845. doi: 10.3389/fimmu.2017.01845. eCollection 2017. Front Immunol. 2017. PMID: 29326719 Free PMC article. Review.

3

Antibodies focused on the human autoantibody immunodominant region are induced by B lymphocytes that constitutively express thyroid peroxidase diverted to the major histocompatibility complex II pathway.

Guo J, McLachlan SM, Rapoport B. Guo J, et al. Among authors: rapoport b. Thyroid. 2006 Apr;16(4):343-9. doi: 10.1089/thy.2006.16.343. Thyroid. 2006. PMID: 16646679

4

Thyroid peroxidase autoantibody epitopes revisited*.

McLachlan SM, Rapoport B. McLachlan SM, et al. Among authors: rapoport b. Clin Endocrinol (Oxf). 2008 Oct;69(4):526-7. doi: 10.1111/j.1365-2265.2008.03246.x. Epub 2008 Mar 19. Clin Endocrinol (Oxf). 2008. PMID: 18363887 No abstract available.

5

Insight into thyroid-stimulating autoantibody interaction with the thyrotropin receptor N-terminus based on mutagenesis and re-evaluation of ambiguity in this region of the receptor crystal structure.

Hamidi S, Chen CR, McLachlan SM, Rapoport B. Hamidi S, et al. Among authors: rapoport b. Thyroid. 2011 Sep;21(9):1013-20. doi: 10.1089/thy.2011.0147. Epub 2011 Aug 11. Thyroid. 2011. PMID: 21834684 Free PMC article.

6

Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa.

McLachlan SM, Rapoport B. McLachlan SM, et al. Among authors: rapoport b. Thyroid. 2013 Jan;23(1):14-24. doi: 10.1089/thy.2012.0374. Thyroid. 2013. PMID: 23025526 Free PMC article. Review.

7

Breaking tolerance to thyroid antigens: changing concepts in thyroid autoimmunity.

McLachlan SM, Rapoport B. McLachlan SM, et al. Among authors: rapoport b. Endocr Rev. 2014 Feb;35(1):59-105. doi: 10.1210/er.2013-1055. Epub 2013 Dec 4. Endocr Rev. 2014. PMID: 24091783 Free PMC article. Review.

8

Graves' hyperthyroidism is antibody-mediated but is predominantly a Th1-type cytokine disease.

Rapoport B, McLachlan SM. Rapoport B, et al. J Clin Endocrinol Metab. 2014 Nov;99(11):4060-1. doi: 10.1210/jc.2014-3011. Epub 2014 Sep 11. J Clin Endocrinol Metab. 2014. PMID: 25210884 Free PMC article. No abstract available.

9

Evidence that TSH Receptor A-Subunit Multimers, Not Monomers, Drive Antibody Affinity Maturation in Graves' Disease.

Rapoport B, Aliesky HA, Chen CR, McLachlan SM. Rapoport B, et al. J Clin Endocrinol Metab. 2015 Jun;100(6):E871-5. doi: 10.1210/jc.2015-1528. Epub 2015 Apr 9. J Clin Endocrinol Metab. 2015. PMID: 25856215 Free PMC article.

10

TSH Receptor Cleavage Into Subunits and Shedding of the A-Subunit; A Molecular and Clinical Perspective.

Rapoport B, McLachlan SM. Rapoport B, et al. Endocr Rev. 2016 Apr;37(2):114-34. doi: 10.1210/er.2015-1098. Epub 2016 Jan 22. Endocr Rev. 2016. PMID: 26799472 Free PMC article. Review.

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