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1-O-Octadecyl-2-O-benzyl-sn-glyceryl-3-phospho-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity.
Carlin AF, Beadle JR, Clark AE, Gully KL, Moreira FR, Baric RS, Graham RL, Valiaeva N, Leibel SL, Bray W, McMillan RE, Freshman JE, Garretson AF, McVicar RN, Rana T, Zhang XQ, Murphy JA, Schooley RT, Hostetler KY. Carlin AF, et al. Among authors: rana t. J Med Chem. 2023 Apr 27;66(8):5802-5819. doi: 10.1021/acs.jmedchem.3c00046. Epub 2023 Apr 11. J Med Chem. 2023. PMID: 37040439 Free PMC article.
Neutralizing Antibody Responses After Severe Acute Respiratory Syndrome Coronavirus 2 BA.2 and BA.2.12.1 Infection Do Not Neutralize BA.4 and BA.5 and Can Be Blunted by Nirmatrelvir/Ritonavir Treatment.
Carlin AF, Clark AE, Garretson AF, Bray W, Porrachia M, Santos AT, Rana TM, Chaillon A, Smith DM. Carlin AF, et al. Among authors: rana tm. Open Forum Infect Dis. 2023 Mar 21;10(4):ofad154. doi: 10.1093/ofid/ofad154. eCollection 2023 Apr. Open Forum Infect Dis. 2023. PMID: 37096144 Free PMC article.
Interferon-Inducible Guanylate-Binding Protein 5 Inhibits Replication of Multiple Viruses by Binding to the Oligosaccharyltransferase Complex and Inhibiting Glycoprotein Maturation.
Wang S, Li W, Wang L, Tiwari SK, Bray W, Wu L, Li N, Hui H, Clark AE, Zhang Q, Zhang L, Carlin AF, Rana TM. Wang S, et al. Among authors: rana tm. bioRxiv [Preprint]. 2024 May 3:2024.05.01.591800. doi: 10.1101/2024.05.01.591800. bioRxiv. 2024. PMID: 38746287 Free PMC article. Preprint.
Induction of neutralizing antibodies against SARS-CoV-2 variants by a multivalent mRNA-lipid nanoparticle vaccine encoding SARS-CoV-2/SARS-CoV Spike protein receptor-binding domains in mice.
Zhang Q, Tiwari S, Wen J, Wang S, Wang L, Li W, Zhang L, Rawling S, Cheng Y, Jokerst J, Rana TM. Zhang Q, et al. Among authors: rana tm. PLoS One. 2024 Apr 18;19(4):e0300524. doi: 10.1371/journal.pone.0300524. eCollection 2024. PLoS One. 2024. PMID: 38635805 Free PMC article.
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes.
F De Jesus D, Zhang Z, Brown NK, Li X, Xiao L, Hu J, Gaffrey MJ, Fogarty G, Kahraman S, Wei J, Basile G, Rana TM, Mathews C, Powers AC, Parent AV, Atkinson MA, Dhe-Paganon S, Eizirik DL, Qian WJ, He C, Kulkarni RN. F De Jesus D, et al. Among authors: rana tm. Nat Cell Biol. 2024 Mar;26(3):421-437. doi: 10.1038/s41556-024-01368-0. Epub 2024 Feb 26. Nat Cell Biol. 2024. PMID: 38409327 Free PMC article.
365 results