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Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells.
Mol Ther. 2023 Aug 2;31(8):2309-2325. doi: 10.1016/j.ymthe.2023.06.006. Epub 2023 Jun 12.
Mol Ther. 2023.
PMID: 37312454
Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells.
Singh N, Frey NV, Engels B, Barrett DM, Shestova O, Ravikumar P, Cummins KD, Lee YG, Pajarillo R, Chun I, Shyu A, Highfill SL, Price A, Zhao L, Peng L, Granda B, Ramones M, Lu XM, Christian DA, Perazzelli J, Lacey SF, Roy NH, Burkhardt JK, Colomb F, Damra M, Abdel-Mohsen M, Liu T, Liu D, Standley DM, Young RM, Brogdon JL, Grupp SA, June CH, Maude SL, Gill S, Ruella M.
Singh N, et al. Among authors: ramones m.
Nat Med. 2021 May;27(5):842-850. doi: 10.1038/s41591-021-01326-5. Epub 2021 Apr 22.
Nat Med. 2021.
PMID: 33888899
Free PMC article.
Clinical Trial.
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Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma.
Johnson LA, Scholler J, Ohkuri T, Kosaka A, Patel PR, McGettigan SE, Nace AK, Dentchev T, Thekkat P, Loew A, Boesteanu AC, Cogdill AP, Chen T, Fraietta JA, Kloss CC, Posey AD Jr, Engels B, Singh R, Ezell T, Idamakanti N, Ramones MH, Li N, Zhou L, Plesa G, Seykora JT, Okada H, June CH, Brogdon JL, Maus MV.
Johnson LA, et al. Among authors: ramones mh.
Sci Transl Med. 2015 Feb 18;7(275):275ra22. doi: 10.1126/scitranslmed.aaa4963.
Sci Transl Med. 2015.
PMID: 25696001
Free PMC article.
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Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice.
Liu X, Jiang S, Fang C, Yang S, Olalere D, Pequignot EC, Cogdill AP, Li N, Ramones M, Granda B, Zhou L, Loew A, Young RM, June CH, Zhao Y.
Liu X, et al. Among authors: ramones m.
Cancer Res. 2015 Sep 1;75(17):3596-607. doi: 10.1158/0008-5472.CAN-15-0159.
Cancer Res. 2015.
PMID: 26330166
Free PMC article.
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Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin.
Xie Y, Zamponi R, Charlat O, Ramones M, Swalley S, Jiang X, Rivera D, Tschantz W, Lu B, Quinn L, Dimitri C, Parker J, Jeffery D, Wilcox SK, Watrobka M, LeMotte P, Granda B, Porter JA, Myer VE, Loew A, Cong F.
Xie Y, et al. Among authors: ramones m.
EMBO Rep. 2013 Dec;14(12):1120-6. doi: 10.1038/embor.2013.167. Epub 2013 Oct 29.
EMBO Rep. 2013.
PMID: 24165923
Free PMC article.
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Incarcerated Spigelian hernia: a rare cause of mechanical small-bowel obstruction.
Ramones MT, Beech D.
Ramones MT, et al.
J Natl Med Assoc. 2010 Aug;102(8):731-3. doi: 10.1016/s0027-9684(15)30646-5.
J Natl Med Assoc. 2010.
PMID: 20806686
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