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DNA methylation aging clocks: challenges and recommendations.
Bell CG, Lowe R, Adams PD, Baccarelli AA, Beck S, Bell JT, Christensen BC, Gladyshev VN, Heijmans BT, Horvath S, Ideker T, Issa JJ, Kelsey KT, Marioni RE, Reik W, Relton CL, Schalkwyk LC, Teschendorff AE, Wagner W, Zhang K, Rakyan VK. Bell CG, et al. Among authors: rakyan vk. Genome Biol. 2019 Nov 25;20(1):249. doi: 10.1186/s13059-019-1824-y. Genome Biol. 2019. PMID: 31767039 Free PMC article. Review.
From genome to epigenome.
Murrell A, Rakyan VK, Beck S. Murrell A, et al. Among authors: rakyan vk. Hum Mol Genet. 2005 Apr 15;14 Spec No 1:R3-R10. doi: 10.1093/hmg/ddi110. Hum Mol Genet. 2005. PMID: 15809270 Review.
Epigenetic variation and inheritance in mammals.
Rakyan VK, Beck S. Rakyan VK, et al. Curr Opin Genet Dev. 2006 Dec;16(6):573-7. doi: 10.1016/j.gde.2006.09.002. Epub 2006 Sep 26. Curr Opin Genet Dev. 2006. PMID: 17005390 Review.
DNA methylation profiling of human chromosomes 6, 20 and 22.
Eckhardt F, Lewin J, Cortese R, Rakyan VK, Attwood J, Burger M, Burton J, Cox TV, Davies R, Down TA, Haefliger C, Horton R, Howe K, Jackson DK, Kunde J, Koenig C, Liddle J, Niblett D, Otto T, Pettett R, Seemann S, Thompson C, West T, Rogers J, Olek A, Berlin K, Beck S. Eckhardt F, et al. Among authors: rakyan vk. Nat Genet. 2006 Dec;38(12):1378-85. doi: 10.1038/ng1909. Epub 2006 Oct 29. Nat Genet. 2006. PMID: 17072317 Free PMC article.
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs).
Rakyan VK, Down TA, Thorne NP, Flicek P, Kulesha E, Gräf S, Tomazou EM, Bäckdahl L, Johnson N, Herberth M, Howe KL, Jackson DK, Miretti MM, Fiegler H, Marioni JC, Birney E, Hubbard TJ, Carter NP, Tavaré S, Beck S. Rakyan VK, et al. Genome Res. 2008 Sep;18(9):1518-29. doi: 10.1101/gr.077479.108. Epub 2008 Jun 24. Genome Res. 2008. PMID: 18577705 Free PMC article.
DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta.
Novakovic B, Wong NC, Sibson M, Ng HK, Morley R, Manuelpillai U, Down T, Rakyan VK, Beck S, Hiendleder S, Roberts CT, Craig JM, Saffery R. Novakovic B, et al. Among authors: rakyan vk. J Biol Chem. 2010 Mar 26;285(13):9583-9593. doi: 10.1074/jbc.M109.064956. Epub 2010 Jan 13. J Biol Chem. 2010. PMID: 20071334 Free PMC article.
64 results