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The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in multiple myeloma.
Crawford LJ, Campbell DC, Morgan JJ, Lawson MA, Down JM, Chauhan D, McAvera RM, Morris TC, Hamilton C, Krishnan A, Rajalingam K, Chantry AD, Irvine AE. Crawford LJ, et al. Among authors: rajalingam k. Oncogene. 2020 Jul;39(27):5001-5014. doi: 10.1038/s41388-020-1345-x. Epub 2020 Jun 10. Oncogene. 2020. PMID: 32523091 Free PMC article.
Ubiquitin-dependent regulation of Cdc42 by XIAP.
Murali A, Shin J, Yurugi H, Krishnan A, Akutsu M, Carpy A, Macek B, Rajalingam K. Murali A, et al. Among authors: rajalingam k. Cell Death Dis. 2017 Jun 29;8(6):e2900. doi: 10.1038/cddis.2017.305. Cell Death Dis. 2017. PMID: 28661476 Free PMC article.
Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas.
Krishnan A, Berthelet J, Renaud E, Rosigkeit S, Distler U, Stawiski E, Wang J, Modrusan Z, Fiedler M, Bienz M, Tenzer S, Schad A, Roth W, Thiede B, Seshagiri S, Musholt TJ, Rajalingam K. Krishnan A, et al. Among authors: rajalingam k. Nat Commun. 2020 Apr 28;11(1):2056. doi: 10.1038/s41467-020-15955-w. Nat Commun. 2020. PMID: 32345963 Free PMC article.
The non-linearity of RAF-MEK signaling in dendritic cells.
Riegel K, Rajalingam K. Riegel K, et al. Among authors: rajalingam k. Cell Cycle. 2020 Sep;19(18):2249-2259. doi: 10.1080/15384101.2020.1795990. Epub 2020 Aug 4. Cell Cycle. 2020. PMID: 32752922 Free PMC article. Review.
ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis.
Bogucka K, Marini F, Rosigkeit S, Schloeder J, Jonuleit H, David K, Schlackow M, Rajalingam K. Bogucka K, et al. Among authors: rajalingam k. Cancer Gene Ther. 2021 May;28(5):359-374. doi: 10.1038/s41417-020-00245-w. Epub 2020 Oct 17. Cancer Gene Ther. 2021. PMID: 33070159
ERK5 modulates IL-6 secretion and contributes to tumor-induced immune suppression.
Riegel K, Yurugi H, Schlöder J, Jonuleit H, Kaulich M, Kirschner F, Arnold-Schild D, Tenzer S, Schild H, Rajalingam K. Riegel K, et al. Among authors: rajalingam k. Cell Death Dis. 2021 Oct 20;12(11):969. doi: 10.1038/s41419-021-04257-8. Cell Death Dis. 2021. PMID: 34671021 Free PMC article.
123 results