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Page 1
Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia.
Kratzer A, Buchebner M, Pfeifer T, Becker TM, Uray G, Miyazaki M, Miyazaki-Anzai S, Ebner B, Chandak PG, Kadam RS, Calayir E, Rathke N, Ahammer H, Radovic B, Trauner M, Hoefler G, Kompella UB, Fauler G, Levi M, Levak-Frank S, Kostner GM, Kratky D. Kratzer A, et al. Among authors: radovic b. J Lipid Res. 2009 Feb;50(2):312-26. doi: 10.1194/jlr.M800376-JLR200. Epub 2008 Sep 23. J Lipid Res. 2009. PMID: 18812595 Free PMC article.
Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Fröhlich E, Magnes C, Sinner F, Haemmerle G, Zechner R, Tabas I, Levak-Frank S, Kratky D. Chandak PG, et al. Among authors: radovic b. J Biol Chem. 2010 Jun 25;285(26):20192-201. doi: 10.1074/jbc.M110.107854. Epub 2010 Apr 27. J Biol Chem. 2010. PMID: 20424161 Free PMC article.
Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice.
Lammers B, Chandak PG, Aflaki E, Van Puijvelde GH, Radovic B, Hildebrand RB, Meurs I, Out R, Kuiper J, Van Berkel TJ, Kolb D, Haemmerle G, Zechner R, Levak-Frank S, Van Eck M, Kratky D. Lammers B, et al. Among authors: radovic b. Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):67-73. doi: 10.1161/ATVBAHA.110.215814. Epub 2010 Oct 28. Arterioscler Thromb Vasc Biol. 2011. PMID: 21030715 Free PMC article.
Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
Aflaki E, Radovic B, Chandak PG, Kolb D, Eisenberg T, Ring J, Fertschai I, Uellen A, Wolinski H, Kohlwein SD, Zechner R, Levak-Frank S, Sattler W, Graier WF, Malli R, Madeo F, Kratky D. Aflaki E, et al. Among authors: radovic b. J Biol Chem. 2011 Mar 4;286(9):7418-28. doi: 10.1074/jbc.M110.175703. Epub 2011 Jan 1. J Biol Chem. 2011. PMID: 21196579 Free PMC article.
Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice.
Chandak PG, Obrowsky S, Radovic B, Doddapattar P, Aflaki E, Kratzer A, Doshi LS, Povoden S, Ahammer H, Hoefler G, Levak-Frank S, Kratky D. Chandak PG, et al. Among authors: radovic b. Biochim Biophys Acta. 2011 Dec;1811(12):1011-20. doi: 10.1016/j.bbalip.2011.08.010. Epub 2011 Sep 1. Biochim Biophys Acta. 2011. PMID: 21924378 Free PMC article.
C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages.
Aflaki E, Doddapattar P, Radović B, Povoden S, Kolb D, Vujić N, Wegscheider M, Koefeler H, Hornemann T, Graier WF, Malli R, Madeo F, Kratky D. Aflaki E, et al. Among authors: radovic b. Cell Death Dis. 2012 Mar 15;3(3):e280. doi: 10.1038/cddis.2012.17. Cell Death Dis. 2012. PMID: 22419109 Free PMC article.
Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice.
Doddapattar P, Radović B, Patankar JV, Obrowsky S, Jandl K, Nusshold C, Kolb D, Vujić N, Doshi L, Chandak PG, Goeritzer M, Ahammer H, Hoefler G, Sattler W, Kratky D. Doddapattar P, et al. Among authors: radovic b. Mol Nutr Food Res. 2013 Oct;57(10):1718-28. doi: 10.1002/mnfr.201200794. Epub 2013 May 3. Mol Nutr Food Res. 2013. PMID: 23650230 Free PMC article.
Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis.
Goeritzer M, Schlager S, Radovic B, Madreiter CT, Rainer S, Thomas G, Lord CC, Sacks J, Brown AL, Vujic N, Obrowsky S, Sachdev V, Kolb D, Chandak PG, Graier WF, Sattler W, Brown JM, Kratky D. Goeritzer M, et al. Among authors: radovic b. J Lipid Res. 2014 Dec;55(12):2562-75. doi: 10.1194/jlr.M052613. Epub 2014 Oct 14. J Lipid Res. 2014. PMID: 25316883 Free PMC article.
39 results