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Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation.
Wu L, Seung E, Xu L, Rao E, Lord DM, Wei RR, Cortez-Retamozo V, Ospina B, Posternak V, Ulinski G, Piepenhagen P, Francesconi E, El-Murr N, Beil C, Kirby P, Li A, Fretland J, Vicente R, Deng G, Dabdoubi T, Cameron B, Bertrand T, Ferrari P, Pouzieux S, Lemoine C, Prades C, Park A, Qiu H, Song Z, Zhang B, Sun F, Chiron M, Rao S, Radošević K, Yang ZY, Nabel GJ. Wu L, et al. Among authors: radosevic k. Nat Cancer. 2020 Jan;1(1):86-98. doi: 10.1038/s43018-019-0004-z. Epub 2019 Nov 18. Nat Cancer. 2020. PMID: 35121834
Complementary epitopes and favorable developability of monoclonal anti-LAMP1 antibodies generated using two transgenic animal platforms.
Cameron B, Dabdoubi T, Berthou-Soulié L, Gagnaire M, Arnould I, Severac A, Soubrier F, Morales J, Leighton PA, Harriman W, Ching K, Abdiche Y, Radošević K, Bouquin T. Cameron B, et al. Among authors: radosevic k. PLoS One. 2020 Jul 16;15(7):e0235815. doi: 10.1371/journal.pone.0235815. eCollection 2020. PLoS One. 2020. PMID: 32673351 Free PMC article.
A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.
Stefano JE, Lord DM, Zhou Y, Jaworski J, Hopke J, Travaline T, Zhang N, Wong K, Lennon A, He T, Bric-Furlong E, Cherrie C, Magnay T, Remy E, Brondyk W, Qiu H, Radošević K. Stefano JE, et al. Among authors: radosevic k. J Biol Chem. 2020 Dec 25;295(52):18379-18389. doi: 10.1074/jbc.RA120.012395. Epub 2020 Oct 29. J Biol Chem. 2020. PMID: 33122192 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33453841
Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific.
Ramasubramanian A, Tennyson R, Magnay M, Kathuria S, Travaline T, Jain A, Lord DM, Salemi M, Sullivan C, Magnay T, Hu J, Bric-Furlong E, Rival P, Zhou Y, Hoffmann D, Brondyk W, Radošević K, Chowdhury PS. Ramasubramanian A, et al. Among authors: radosevic k. Antibodies (Basel). 2020 Nov 6;9(4):62. doi: 10.3390/antib9040062. Antibodies (Basel). 2020. PMID: 33172091 Free PMC article.
84 results