Rabinowitz JD - Search Results

1

A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway.

Ghergurovich JM, García-Cañaveras JC, Wang J, Schmidt E, Zhang Z, TeSlaa T, Patel H, Chen L, Britt EC, Piqueras-Nebot M, Gomez-Cabrera MC, Lahoz A, Fan J, Beier UH, Kim H, Rabinowitz JD. Ghergurovich JM, et al. Among authors: rabinowitz jd. Nat Chem Biol. 2020 Jul;16(7):731-739. doi: 10.1038/s41589-020-0533-x. Epub 2020 May 11. Nat Chem Biol. 2020. PMID: 32393898 Free PMC article.

2

A domino effect in antifolate drug action in Escherichia coli.

Kwon YK, Lu W, Melamud E, Khanam N, Bognar A, Rabinowitz JD. Kwon YK, et al. Among authors: rabinowitz jd. Nat Chem Biol. 2008 Oct;4(10):602-8. doi: 10.1038/nchembio.108. Epub 2008 Aug 24. Nat Chem Biol. 2008. PMID: 18724364 Free PMC article.

3

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli.

Bennett BD, Kimball EH, Gao M, Osterhout R, Van Dien SJ, Rabinowitz JD. Bennett BD, et al. Among authors: rabinowitz jd. Nat Chem Biol. 2009 Aug;5(8):593-9. doi: 10.1038/nchembio.186. Epub 2009 Jun 28. Nat Chem Biol. 2009. PMID: 19561621 Free PMC article.

4

The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.

Kelly RC, Bolitho ME, Higgins DA, Lu W, Ng WL, Jeffrey PD, Rabinowitz JD, Semmelhack MF, Hughson FM, Bassler BL. Kelly RC, et al. Among authors: rabinowitz jd. Nat Chem Biol. 2009 Dec;5(12):891-5. doi: 10.1038/nchembio.237. Epub 2009 Oct 18. Nat Chem Biol. 2009. PMID: 19838203 Free PMC article.

5

Systems-level metabolic flux profiling elucidates a complete, bifurcated tricarboxylic acid cycle in Clostridium acetobutylicum.

Amador-Noguez D, Feng XJ, Fan J, Roquet N, Rabitz H, Rabinowitz JD. Amador-Noguez D, et al. Among authors: rabinowitz jd. J Bacteriol. 2010 Sep;192(17):4452-61. doi: 10.1128/JB.00490-10. Epub 2010 Jul 9. J Bacteriol. 2010. PMID: 20622067 Free PMC article.

6

α-Ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition.

Doucette CD, Schwab DJ, Wingreen NS, Rabinowitz JD. Doucette CD, et al. Among authors: rabinowitz jd. Nat Chem Biol. 2011 Oct 16;7(12):894-901. doi: 10.1038/nchembio.685. Nat Chem Biol. 2011. PMID: 22002719 Free PMC article.

7

Liquid chromatography-high resolution mass spectrometry analysis of fatty acid metabolism.

Kamphorst JJ, Fan J, Lu W, White E, Rabinowitz JD. Kamphorst JJ, et al. Among authors: rabinowitz jd. Anal Chem. 2011 Dec 1;83(23):9114-22. doi: 10.1021/ac202220b. Epub 2011 Nov 4. Anal Chem. 2011. PMID: 22004349 Free PMC article.

8

Teaching the design principles of metabolism.

Rabinowitz JD, Vastag L. Rabinowitz JD, et al. Nat Chem Biol. 2012 May 17;8(6):497-501. doi: 10.1038/nchembio.969. Nat Chem Biol. 2012. PMID: 22596190 Free PMC article.

9

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids.

Kamphorst JJ, Cross JR, Fan J, de Stanchina E, Mathew R, White EP, Thompson CB, Rabinowitz JD. Kamphorst JJ, et al. Among authors: rabinowitz jd. Proc Natl Acad Sci U S A. 2013 May 28;110(22):8882-7. doi: 10.1073/pnas.1307237110. Epub 2013 May 13. Proc Natl Acad Sci U S A. 2013. PMID: 23671091 Free PMC article.

10

Fatty acid labeling from glutamine in hypoxia can be explained by isotope exchange without net reductive isocitrate dehydrogenase (IDH) flux.

Fan J, Kamphorst JJ, Rabinowitz JD, Shlomi T. Fan J, et al. Among authors: rabinowitz jd. J Biol Chem. 2013 Oct 25;288(43):31363-9. doi: 10.1074/jbc.M113.502740. Epub 2013 Sep 12. J Biol Chem. 2013. PMID: 24030823 Free PMC article.

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