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Ligase 3-mediated end-joining maintains genome stability of human embryonic stem cells.
Kohutova A, Raška J, Kruta M, Seneklova M, Barta T, Fojtik P, Jurakova T, Walter CA, Hampl A, Dvorak P, Rotrekl V. Kohutova A, et al. Among authors: raska j. FASEB J. 2019 Jun;33(6):6778-6788. doi: 10.1096/fj.201801877RR. Epub 2019 Feb 26. FASEB J. 2019. PMID: 30807703
DSBs in hESCs are also repaired via homologous recombination (HR); however, DSB overload, together with massive end protection by 53BP1, triggers competition between error-free HR and mutagenic nonhomologous EJ.-Kohutova, A., Raska, J., Kruta, M., Seneklova, M., Bar …
DSBs in hESCs are also repaired via homologous recombination (HR); however, DSB overload, together with massive end protection by 53BP1, tri …
Mutation frequency dynamics in HPRT locus in culture-adapted human embryonic stem cells and induced pluripotent stem cells correspond to their differentiated counterparts.
Krutá M, Šeneklová M, Raška J, Salykin A, Zerzánková L, Pešl M, Bártová E, Franek M, Baumeisterová A, Košková S, Neelsen KJ, Hampl A, Dvořák P, Rotrekl V. Krutá M, et al. Among authors: raska j. Stem Cells Dev. 2014 Oct 15;23(20):2443-54. doi: 10.1089/scd.2013.0611. Epub 2014 Jul 25. Stem Cells Dev. 2014. PMID: 24836366 Free PMC article.
Cerebral organoids derived from patients with Alzheimer's disease with PSEN1/2 mutations have defective tissue patterning and altered development.
Vanova T, Sedmik J, Raska J, Amruz Cerna K, Taus P, Pospisilova V, Nezvedova M, Fedorova V, Kadakova S, Klimova H, Capandova M, Orviska P, Fojtik P, Bartova S, Plevova K, Spacil Z, Hribkova H, Bohaciakova D. Vanova T, et al. Among authors: raska j. Cell Rep. 2023 Nov 28;42(11):113310. doi: 10.1016/j.celrep.2023.113310. Epub 2023 Oct 20. Cell Rep. 2023. PMID: 37864790 Free article.
30 results