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APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer's cases.
Perez-Corredor P, Vanderleest TE, Vacano GN, Sanchez JS, Villalba-Moreno ND, Marino C, Krasemann S, Mendivil-Perez MA, Aguillón D, Jiménez-Del-Río M, Baena A, Sepulveda-Falla D, Lopera F, Quiroz YT, Arboleda-Velasquez JF, Mazzarino RC. Perez-Corredor P, et al. Front Mol Neurosci. 2024 Mar 20;17:1373568. doi: 10.3389/fnmol.2024.1373568. eCollection 2024. Front Mol Neurosci. 2024. PMID: 38571814 Free PMC article.
APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation.
Marino C, Perez-Corredor P, O'Hare M, Heuer A, Chmielewska N, Gordon H, Chandrahas AS, Gonzalez-Buendia L, Delgado-Tirado S, Doan TH, Vanderleest TE, Arevalo-Alquichire S, Obar RA, Ortiz-Cordero C, Villegas A, Sepulveda-Falla D, Kim LA, Lopera F, Mahley R, Huang Y, Quiroz YT, Arboleda-Velasquez JF. Marino C, et al. Alzheimers Dement. 2024 Feb;20(2):819-836. doi: 10.1002/alz.13436. Epub 2023 Oct 4. Alzheimers Dement. 2024. PMID: 37791598 Free PMC article.
Sex differences in blood biomarkers and cognitive performance in individuals with autosomal dominant Alzheimer's disease.
Vila-Castelar C, Chen Y, Langella S, Lopera F, Zetterberg H, Hansson O, Dage JL, Janelidzde S, Su Y, Chen K, Pluim McDowell C, Martinez JE, Ramirez-Gomez L, Garcia G, Aguillon D, Baena A, Giraldo-Chica M, Protas HD, Ghisays V, Rios-Romenets S, Tariot PN, Blennow K, Reiman EM, Quiroz YT. Vila-Castelar C, et al. Alzheimers Dement. 2023 Sep;19(9):4127-4138. doi: 10.1002/alz.13314. Epub 2023 Jun 6. Alzheimers Dement. 2023. PMID: 37279390
Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man.
Lopera F, Marino C, Chandrahas AS, O'Hare M, Villalba-Moreno ND, Aguillon D, Baena A, Sanchez JS, Vila-Castelar C, Ramirez Gomez L, Chmielewska N, Oliveira GM, Littau JL, Hartmann K, Park K, Krasemann S, Glatzel M, Schoemaker D, Gonzalez-Buendia L, Delgado-Tirado S, Arevalo-Alquichire S, Saez-Torres KL, Amarnani D, Kim LA, Mazzarino RC, Gordon H, Bocanegra Y, Villegas A, Gai X, Bootwalla M, Ji J, Shen L, Kosik KS, Su Y, Chen Y, Schultz A, Sperling RA, Johnson K, Reiman EM, Sepulveda-Falla D, Arboleda-Velasquez JF, Quiroz YT. Lopera F, et al. Nat Med. 2023 May;29(5):1243-1252. doi: 10.1038/s41591-023-02318-3. Epub 2023 May 15. Nat Med. 2023. PMID: 37188781 Free PMC article.
Associations of category fluency clustering performance with in vivo brain pathology in autosomal dominant Alzheimer's disease.
Yucebas D, Fox-Fuller JT, Badillo Cabrera A, Baena A, Pluim McDowell C, Aduen P, Vila-Castelar C, Bocanegra Y, Tirado V, Sanchez JS, Cronin-Golomb A, Lopera F, Quiroz YT. Yucebas D, et al. J Int Neuropsychol Soc. 2024 Jan;30(1):77-83. doi: 10.1017/S1355617723000243. Epub 2023 Apr 26. J Int Neuropsychol Soc. 2024. PMID: 37185154 Free PMC article.
Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease.
Aguillon D, Langella S, Chen Y, Sanchez JS, Su Y, Vila-Castelar C, Vasquez D, Zetterberg H, Hansson O, Dage JL, Janelidze S, Chen K, Fox-Fuller JT, Aduen P, Martinez JE, Garcia G, Baena A, Guzman C, Johnson KA, Sperling RA, Blennow K, Reiman EM, Lopera F, Quiroz YT. Aguillon D, et al. Alzheimers Dement. 2023 Jun;19(6):2585-2594. doi: 10.1002/alz.12906. Epub 2022 Dec 26. Alzheimers Dement. 2023. PMID: 36571821