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Cell type-specific roles of APOE4 in Alzheimer disease.
Blumenfeld J, Yip O, Kim MJ, Huang Y. Blumenfeld J, et al. Nat Rev Neurosci. 2024 Feb;25(2):91-110. doi: 10.1038/s41583-023-00776-9. Epub 2024 Jan 8. Nat Rev Neurosci. 2024. PMID: 38191720 Free PMC article. Review.
The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation.
Nelson MR, Liu P, Agrawal A, Yip O, Blumenfeld J, Traglia M, Kim MJ, Koutsodendris N, Rao A, Grone B, Hao Y, Yoon SY, Xu Q, De Leon S, Choenyi T, Thomas R, Lopera F, Quiroz YT, Arboleda-Velasquez JF, Reiman EM, Mahley RW, Huang Y. Nelson MR, et al. Nat Neurosci. 2023 Dec;26(12):2104-2121. doi: 10.1038/s41593-023-01480-8. Epub 2023 Nov 13. Nat Neurosci. 2023. PMID: 37957317 Free PMC article.